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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC4
All Species:
28.79
Human Site:
T421
Identified Species:
57.58
UniProt:
Q96A65
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A65
NP_068579.3
974
110498
T421
A
Q
L
S
Y
A
S
T
G
R
E
F
A
A
F
Chimpanzee
Pan troglodytes
XP_001139207
974
110510
T421
A
Q
L
S
Y
A
S
T
G
R
E
F
A
A
F
Rhesus Macaque
Macaca mulatta
XP_001101461
556
63519
D71
A
Y
E
K
C
D
R
D
L
D
E
L
I
V
Q
Dog
Lupus familis
XP_539369
975
110615
T422
A
Q
L
S
Y
A
S
T
G
R
D
F
A
A
F
Cat
Felis silvestris
Mouse
Mus musculus
O35382
975
110526
T422
A
Q
L
S
Y
A
S
T
G
R
E
F
A
A
F
Rat
Rattus norvegicus
Q62824
975
110534
T422
A
Q
L
S
Y
A
S
T
G
R
E
F
A
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511490
951
106803
E466
K
N
T
R
T
A
S
E
P
S
A
Q
L
S
Y
Chicken
Gallus gallus
XP_414996
976
111102
S423
T
Q
L
S
Y
A
S
S
G
R
E
F
A
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025305
968
109680
T415
A
Q
L
S
Y
A
S
T
G
G
D
F
G
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNH6
985
111648
S412
T
G
F
S
E
P
T
S
N
I
N
S
Y
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWS2
893
100996
R393
N
V
L
G
T
A
S
R
K
Q
L
F
R
F
E
Sea Urchin
Strong. purpuratus
XP_796621
637
72763
S152
Q
K
Q
E
F
Y
G
S
D
G
Q
V
L
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
49.3
96.9
N.A.
95.7
95.2
N.A.
85.4
89.7
N.A.
80.4
N.A.
35.3
N.A.
27.3
33.5
Protein Similarity:
100
99.9
52.2
98.3
N.A.
97.8
97.6
N.A.
89
94.8
N.A.
88.8
N.A.
57.4
N.A.
48.9
47.6
P-Site Identity:
100
100
13.3
93.3
N.A.
100
100
N.A.
13.3
86.6
N.A.
80
N.A.
6.6
N.A.
26.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
26.6
93.3
N.A.
86.6
N.A.
20
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
75
0
0
0
0
9
0
50
67
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
9
9
17
0
0
0
0
% D
% Glu:
0
0
9
9
9
0
0
9
0
0
50
0
0
0
17
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
67
0
17
59
% F
% Gly:
0
9
0
9
0
0
9
0
59
17
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% I
% Lys:
9
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
67
0
0
0
0
0
9
0
9
9
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
59
9
0
0
0
0
0
0
9
9
9
0
0
9
% Q
% Arg:
0
0
0
9
0
0
9
9
0
50
0
0
9
0
0
% R
% Ser:
0
0
0
67
0
0
75
25
0
9
0
9
0
9
0
% S
% Thr:
17
0
9
0
17
0
9
50
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
59
9
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _