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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXW5 All Species: 16.67
Human Site: Y54 Identified Species: 73.33
UniProt: Q969U6 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969U6 NP_061871.1 566 63922 Y54 R E Q F Y R Y Y Q V A R D V P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117846 503 56509 H39 V L H L S F S H S G Y Q F A S
Dog Lupus familis XP_548364 566 63777 Y54 R E Q F Y R Y Y Q V A R D V P
Cat Felis silvestris
Mouse Mus musculus Q9QXW2 573 64628 Y54 K E Q F Y R Y Y Q V A R D V P
Rat Rattus norvegicus Q4KLI9 569 64016 Y54 R E Q F Y R Y Y Q V A R D V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395619 703 81507 Y128 K D L F Y Q T Y K I D P D I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 86.2 91.1 N.A. 88.8 89.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 38.5 N.A. N.A.
Protein Similarity: 100 N.A. 87.4 94.8 N.A. 92.1 92.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 54.4 N.A. N.A.
P-Site Identity: 100 N.A. 0 100 N.A. 93.3 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 67 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 0 0 0 17 0 84 0 0 % D
% Glu: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 84 0 17 0 0 0 0 0 0 17 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 17 % G
% His: 0 0 17 0 0 0 0 17 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 17 0 0 0 17 0 % I
% Lys: 34 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % K
% Leu: 0 17 17 17 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 67 % P
% Gln: 0 0 67 0 0 17 0 0 67 0 0 17 0 0 0 % Q
% Arg: 50 0 0 0 0 67 0 0 0 0 0 67 0 0 0 % R
% Ser: 0 0 0 0 17 0 17 0 17 0 0 0 0 0 17 % S
% Thr: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 0 67 0 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 84 0 67 84 0 0 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _