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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC10
All Species:
36.67
Human Site:
Y191
Identified Species:
67.22
UniProt:
Q969S8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969S8
NP_001152758.1
669
71445
Y191
E
D
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Chimpanzee
Pan troglodytes
XP_515218
669
71461
Y191
E
D
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Rhesus Macaque
Macaca mulatta
XP_001112365
671
71733
Y191
E
D
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Dog
Lupus familis
XP_848669
830
88564
Y191
E
D
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P3E7
666
72091
Y191
N
D
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Rat
Rattus norvegicus
Q569C4
588
63939
F144
Q
R
A
A
A
N
G
F
C
V
F
N
N
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509232
334
36373
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089352
683
76715
Y193
E
E
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Zebra Danio
Brachydanio rerio
NP_956069
676
74999
Y193
E
E
D
P
S
V
L
Y
F
S
W
H
R
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727843
1138
125987
Y303
Y
N
D
P
R
V
V
Y
F
S
I
H
R
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20296
955
106730
Y201
Y
D
D
K
R
V
L
Y
F
S
I
H
R
H
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LRK8
682
76616
I250
W
K
D
S
R
V
L
I
F
S
V
H
R
H
D
Baker's Yeast
Sacchar. cerevisiae
P53973
706
80051
Y264
Y
Q
D
D
Q
V
L
Y
V
S
L
H
R
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.2
63.8
N.A.
75.4
66.3
N.A.
33
N.A.
48.6
45.1
N.A.
26.1
N.A.
23
N.A.
Protein Similarity:
100
99.4
97.1
69.8
N.A.
83.2
72.8
N.A.
40.2
N.A.
65
61.3
N.A.
36.7
N.A.
39.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
0
N.A.
93.3
93.3
N.A.
60
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
0
N.A.
100
100
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.1
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.7
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
47
85
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
47
16
0
0
0
0
0
0
0
0
0
0
0
0
77
% E
% Phe:
0
0
0
0
0
0
0
8
77
0
8
0
0
16
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
85
0
16
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
77
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
8
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
24
0
0
0
0
0
0
0
85
0
0
% R
% Ser:
0
0
0
8
54
0
0
0
0
85
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
85
8
0
8
8
8
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% W
% Tyr:
24
0
0
0
0
0
0
77
0
0
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _