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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF622
All Species:
12.73
Human Site:
Y376
Identified Species:
25.45
UniProt:
Q969S3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969S3
NP_219482.1
477
54272
Y376
P
S
E
K
N
L
E
Y
D
D
E
T
M
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536521
467
52265
Y366
P
S
E
K
T
V
E
Y
D
D
E
T
M
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91VY9
476
53433
C375
S
T
D
K
I
L
E
C
D
D
E
T
M
E
L
Rat
Rattus norvegicus
Q7TM96
386
43871
G293
K
Y
L
G
E
K
V
G
V
G
K
I
C
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510899
470
52048
Y369
P
A
E
K
N
L
E
Y
D
D
D
S
M
E
L
Chicken
Gallus gallus
Q90Y35
405
46090
A312
K
S
F
Y
S
T
E
A
V
Q
A
H
M
N
D
Frog
Xenopus laevis
NP_001080550
467
53394
Y366
G
S
D
K
T
L
E
Y
N
D
D
T
M
E
M
Zebra Danio
Brachydanio rerio
XP_694322
494
56322
F391
P
D
D
K
T
V
E
F
D
D
E
T
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573252
409
47060
L315
L
D
G
D
E
Y
Q
L
V
L
P
S
G
A
V
Honey Bee
Apis mellifera
XP_394767
381
44548
L288
L
D
D
S
D
Y
Q
L
I
L
P
S
G
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200563
437
49556
M337
M
D
L
G
S
C
E
M
K
E
E
G
F
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38344
393
45816
N300
L
P
Q
E
Y
L
Y
N
D
G
I
E
L
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
78.6
N.A.
82.8
70.2
N.A.
50.9
60.7
68.7
62.5
N.A.
41.7
40.2
N.A.
42.1
Protein Similarity:
100
N.A.
N.A.
86.5
N.A.
89
75.4
N.A.
62.4
72.5
82.1
74.9
N.A.
59.5
58
N.A.
58.7
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
66.6
0
N.A.
80
20
60
60
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
80
6.6
N.A.
100
26.6
86.6
86.6
N.A.
20
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
9
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
34
34
9
9
0
0
0
50
50
17
0
0
0
9
% D
% Glu:
0
0
25
9
17
0
67
0
0
9
42
9
0
59
0
% E
% Phe:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% F
% Gly:
9
0
9
17
0
0
0
9
0
17
0
9
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
0
0
0
9
0
0
0
9
0
9
9
0
0
9
% I
% Lys:
17
0
0
50
0
9
0
0
9
0
9
0
0
0
0
% K
% Leu:
25
0
17
0
0
42
0
17
0
17
0
0
17
9
59
% L
% Met:
9
0
0
0
0
0
0
9
0
0
0
0
50
0
9
% M
% Asn:
0
0
0
0
17
0
0
9
9
0
0
0
0
17
0
% N
% Pro:
34
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
17
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
34
0
9
17
0
0
0
0
0
0
25
0
0
0
% S
% Thr:
0
9
0
0
25
9
0
0
0
0
0
42
0
0
0
% T
% Val:
0
0
0
0
0
17
9
0
25
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
9
0
9
9
17
9
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _