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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF622 All Species: 0.61
Human Site: T168 Identified Species: 1.21
UniProt: Q969S3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q969S3 NP_219482.1 477 54272 T168 V G T G G R G T H D R D P S E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536521 467 52265 P167 P A A P D R P P R L Q W F E Q
Cat Felis silvestris
Mouse Mus musculus Q91VY9 476 53433 V167 A A A G A R G V P E R D P T E
Rat Rattus norvegicus Q7TM96 386 43871 K116 M N E K N L E K G L G V D S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510899 470 52048 R174 L P R P W L V R R L R R L G D
Chicken Gallus gallus Q90Y35 405 46090 A135 M N A A I Q Q A I R A Q P S S
Frog Xenopus laevis NP_001080550 467 53394 R167 D N E G A S A R P E K P P R Q
Zebra Danio Brachydanio rerio XP_694322 494 56322 K192 S K A T P T E K Q V R E R P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573252 409 47060 A136 H P A L A A A A A G K G R L A
Honey Bee Apis mellifera XP_394767 381 44548 S111 E I V N E D L S D D G P S E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200563 437 49556 K142 M R E G A E K K K E L K I E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38344 393 45816 E123 K L S L Q E N E E N K E K E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 78.6 N.A. 82.8 70.2 N.A. 50.9 60.7 68.7 62.5 N.A. 41.7 40.2 N.A. 42.1
Protein Similarity: 100 N.A. N.A. 86.5 N.A. 89 75.4 N.A. 62.4 72.5 82.1 74.9 N.A. 59.5 58 N.A. 58.7
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 46.6 6.6 N.A. 6.6 13.3 13.3 6.6 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 20 N.A. 60 13.3 N.A. 20 26.6 33.3 20 N.A. 6.6 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 42 9 34 9 17 17 9 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 9 0 0 9 17 0 17 9 0 25 % D
% Glu: 9 0 25 0 9 17 17 9 9 25 0 17 0 34 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 9 0 34 9 0 17 0 9 9 17 9 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 9 9 0 9 0 0 9 25 9 0 25 9 9 0 0 % K
% Leu: 9 9 0 17 0 17 9 0 0 25 9 0 9 9 0 % L
% Met: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 25 0 9 9 0 9 0 0 9 0 0 0 0 0 % N
% Pro: 9 17 0 17 9 0 9 9 17 0 0 17 34 9 0 % P
% Gln: 0 0 0 0 9 9 9 0 9 0 9 9 0 0 17 % Q
% Arg: 0 9 9 0 0 25 0 17 17 9 34 9 17 9 0 % R
% Ser: 9 0 9 0 0 9 0 9 0 0 0 0 9 25 17 % S
% Thr: 0 0 9 9 0 9 0 9 0 0 0 0 0 9 0 % T
% Val: 9 0 9 0 0 0 9 9 0 9 0 9 0 0 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _