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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEIL2
All Species:
16.36
Human Site:
S185
Identified Species:
51.43
UniProt:
Q969S2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969S2
NP_001129218.1
332
36826
S185
Y
N
C
Q
L
S
W
S
S
S
P
V
V
T
P
Chimpanzee
Pan troglodytes
XP_001142056
384
41932
S219
Y
N
C
Q
L
S
W
S
S
S
P
V
V
T
P
Rhesus Macaque
Macaca mulatta
XP_001086780
332
36580
S185
Y
N
C
Q
M
S
W
S
S
S
P
V
V
T
P
Dog
Lupus familis
XP_543204
504
55251
R356
Y
N
C
Q
M
S
W
R
S
S
A
L
V
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6R2P8
329
36801
S181
Y
N
C
Q
M
S
W
S
X
X
P
V
I
E
P
Rat
Rattus norvegicus
NP_001100740
330
36816
S182
Y
N
C
Q
M
S
W
S
P
P
P
V
I
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521074
191
20640
P61
S
P
D
T
S
L
T
P
G
M
A
Q
P
Q
S
Chicken
Gallus gallus
XP_420042
328
35944
C179
Y
N
C
R
M
H
W
C
S
S
L
V
A
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
91.5
48.8
N.A.
72.8
73.4
N.A.
29.8
54.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.9
93.9
52.9
N.A.
79.2
79.2
N.A.
37.9
64.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
66.6
66.6
N.A.
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
25
0
13
0
0
% A
% Cys:
0
0
88
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
25
13
0
0
0
0
13
13
0
0
0
% L
% Met:
0
0
0
0
63
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
88
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
13
13
13
63
0
13
0
88
% P
% Gln:
0
0
0
75
0
0
0
0
0
0
0
13
0
25
0
% Q
% Arg:
0
0
0
13
0
0
0
13
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
13
75
0
63
63
63
0
0
0
0
13
% S
% Thr:
0
0
0
13
0
0
13
0
0
0
0
0
0
38
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
75
50
0
0
% V
% Trp:
0
0
0
0
0
0
88
0
0
0
0
0
0
0
0
% W
% Tyr:
88
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _