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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
L3MBTL2
All Species:
44.55
Human Site:
Y589
Identified Species:
89.09
UniProt:
Q969R5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969R5
NP_113676.2
705
79110
Y589
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Chimpanzee
Pan troglodytes
XP_001168767
705
79052
Y589
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Rhesus Macaque
Macaca mulatta
XP_001103491
705
78955
Y589
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Dog
Lupus familis
XP_538356
707
79354
Y591
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P59178
703
78936
Y589
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Rat
Rattus norvegicus
Q3MIF2
703
78948
Y589
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518844
715
80288
Y594
D
C
E
S
P
D
I
Y
A
V
G
W
C
E
L
Chicken
Gallus gallus
NP_001006238
723
81164
Y606
D
C
E
S
P
D
I
Y
P
V
G
W
C
E
L
Frog
Xenopus laevis
Q32N90
621
69793
F515
K
D
V
P
N
H
G
F
R
V
G
M
K
L
E
Zebra Danio
Brachydanio rerio
NP_956326
805
90717
Y667
D
C
Q
S
P
E
I
Y
P
V
G
W
C
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK33
1220
133648
Y960
D
C
E
S
A
D
I
Y
P
V
G
W
C
V
L
Honey Bee
Apis mellifera
XP_397193
889
100688
Y638
D
C
Q
S
P
D
I
Y
P
V
G
W
C
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
95.7
N.A.
91.2
91.7
N.A.
83.5
77.8
51.4
48.3
N.A.
28.4
31.8
N.A.
N.A.
Protein Similarity:
100
99.8
99
97.4
N.A.
95
94.7
N.A.
90.6
86.4
65.6
62.3
N.A.
40.4
46.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
13.3
80
N.A.
86.6
86.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
20
100
N.A.
86.6
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
92
0
0
0
0
0
0
0
0
0
0
92
0
0
% C
% Asp:
92
9
0
0
0
84
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
75
0
0
9
0
0
0
0
0
0
0
75
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
100
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
84
0
0
0
84
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
92
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
100
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
92
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _