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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKB All Species: 32.73
Human Site: Y409 Identified Species: 60
UniProt: Q93100 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93100 NP_000284.1 1093 124884 Y409 G Y P V V P K Y Y Y V P A D F
Chimpanzee Pan troglodytes XP_001162360 1093 124839 Y409 G Y P V V P K Y Y Y V P A D F
Rhesus Macaque Macaca mulatta XP_001113858 1093 124900 Y409 G Y P V V P K Y Y Y V P A D F
Dog Lupus familis XP_863764 1086 123962 Y402 G Y P V I P K Y Y Y V P A D F
Cat Felis silvestris
Mouse Mus musculus Q7TSH2 1085 123871 Y401 G Y P V V P K Y Y Y V P A D F
Rat Rattus norvegicus Q64649 1242 139137 S406 L P H M W G Q S L Y I L G N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507442 1100 125727 Y416 G Y P V I P K Y Y Y V P A D F
Chicken Gallus gallus NP_001007832 1086 123548 Y402 G C P V V P K Y Y Y V P A D F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698197 1087 124284 Y404 G H A V I P K Y Y H V P A D F
Tiger Blowfish Takifugu rubipres Q9W6R1 1229 137905 Q458 I K A L L S E Q G M V V Q T V
Fruit Fly Dros. melanogaster Q9VLS1 1093 124845 N402 R C L R T D V N G D P V V T M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34335 1226 139432 F474 V D E I D P V F T I L P A S A
Sea Urchin Strong. purpuratus XP_796888 681 77973 T82 Y D L N T G N T Q P D N Y H H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.5 94.1 N.A. 90.6 30.5 N.A. 88.5 83.3 N.A. 78.9 31.7 46.5 N.A. 29.6 35.5
Protein Similarity: 100 100 99.7 96.3 N.A. 94.3 50 N.A. 93.4 91.1 N.A. 88.5 50.6 65.6 N.A. 48.6 47.2
P-Site Identity: 100 100 100 93.3 N.A. 100 6.6 N.A. 93.3 93.3 N.A. 73.3 6.6 0 N.A. 20 0
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 100 93.3 N.A. 93.3 26.6 0 N.A. 40 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 0 0 0 0 0 0 0 70 0 8 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 0 8 8 0 0 0 8 8 0 0 62 0 % D
% Glu: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 62 % F
% Gly: 62 0 0 0 0 16 0 0 16 0 0 0 8 0 0 % G
% His: 0 8 8 0 0 0 0 0 0 8 0 0 0 8 8 % H
% Ile: 8 0 0 8 24 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 62 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 16 8 8 0 0 0 8 0 8 8 0 0 8 % L
% Met: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 8 % M
% Asn: 0 0 0 8 0 0 8 8 0 0 0 8 0 8 0 % N
% Pro: 0 8 54 0 0 70 0 0 0 8 8 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 8 0 0 0 8 0 0 % Q
% Arg: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 8 0 8 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 16 0 0 8 8 0 0 0 0 16 0 % T
% Val: 8 0 0 62 39 0 16 0 0 0 70 16 8 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 47 0 0 0 0 0 62 62 62 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _