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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKB All Species: 11.82
Human Site: T22 Identified Species: 21.67
UniProt: Q93100 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93100 NP_000284.1 1093 124884 T22 V L E R R A R T K R S G S V Y
Chimpanzee Pan troglodytes XP_001162360 1093 124839 T22 V L E R R A R T K R S G S V Y
Rhesus Macaque Macaca mulatta XP_001113858 1093 124900 T22 V L E R R A R T K R S G S V Y
Dog Lupus familis XP_863764 1086 123962 P24 R S G S V Y E P L K S I N L P
Cat Felis silvestris
Mouse Mus musculus Q7TSH2 1085 123871 P23 R S G S V Y E P L K S I N L P
Rat Rattus norvegicus Q64649 1242 139137 G32 C H Q N P V T G L L P A S Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507442 1100 125727 A29 D G F C G R E A Q L K S S V Y
Chicken Gallus gallus NP_001007832 1086 123548 Y22 F L R C G S I Y E P L K S I N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698197 1087 124284 S23 A R S K R S G S I Y E P L K L
Tiger Blowfish Takifugu rubipres Q9W6R1 1229 137905 W43 S V Q K K D A W V R D N V Y S
Fruit Fly Dros. melanogaster Q9VLS1 1093 124845 D23 G G S S G A P D S G R H N S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34335 1226 139432 V49 H A W V R D N V Y I A Q A L W
Sea Urchin Strong. purpuratus XP_796888 681 77973
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.5 94.1 N.A. 90.6 30.5 N.A. 88.5 83.3 N.A. 78.9 31.7 46.5 N.A. 29.6 35.5
Protein Similarity: 100 100 99.7 96.3 N.A. 94.3 50 N.A. 93.4 91.1 N.A. 88.5 50.6 65.6 N.A. 48.6 47.2
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. 20 13.3 N.A. 6.6 6.6 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 100 26.6 N.A. 26.6 13.3 N.A. 26.6 33.3 N.A. 26.6 33.3 13.3 N.A. 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 31 8 8 0 0 8 8 8 0 0 % A
% Cys: 8 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 16 0 8 0 0 8 0 0 0 8 % D
% Glu: 0 0 24 0 0 0 24 0 8 0 8 0 0 0 0 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 16 16 0 24 0 8 8 0 8 0 24 0 0 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 8 0 16 0 8 0 % I
% Lys: 0 0 0 16 8 0 0 0 24 16 8 8 0 8 0 % K
% Leu: 0 31 0 0 0 0 0 0 24 16 8 0 8 24 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 0 0 8 24 0 8 % N
% Pro: 0 0 0 0 8 0 8 16 0 8 8 8 0 0 16 % P
% Gln: 0 0 16 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 16 8 8 24 39 8 24 0 0 31 8 0 0 0 0 % R
% Ser: 8 16 16 24 0 16 0 8 8 0 39 8 47 8 8 % S
% Thr: 0 0 0 0 0 0 8 24 0 0 0 0 0 0 0 % T
% Val: 24 8 0 8 16 8 0 8 8 0 0 0 8 31 0 % V
% Trp: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 16 0 8 8 8 0 0 0 16 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _