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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHKB
All Species:
36.06
Human Site:
S281
Identified Species:
66.11
UniProt:
Q93100
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93100
NP_000284.1
1093
124884
S281
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Chimpanzee
Pan troglodytes
XP_001162360
1093
124839
S281
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Rhesus Macaque
Macaca mulatta
XP_001113858
1093
124900
S281
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Dog
Lupus familis
XP_863764
1086
123962
S274
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSH2
1085
123871
S273
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Rat
Rattus norvegicus
Q64649
1242
139137
I284
V
E
I
T
K
Q
E
I
I
T
K
L
Q
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507442
1100
125727
S288
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Chicken
Gallus gallus
NP_001007832
1086
123548
S274
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698197
1087
124284
S276
R
N
R
Q
T
L
C
S
L
L
P
R
E
S
R
Tiger Blowfish
Takifugu rubipres
Q9W6R1
1229
137905
T309
H
C
P
K
E
D
P
T
R
L
H
Y
D
P
A
Fruit Fly
Dros. melanogaster
Q9VLS1
1093
124845
T282
R
N
R
S
I
F
E
T
M
L
P
R
E
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34335
1226
139432
E323
K
S
E
L
Q
Q
F
E
D
I
E
C
E
W
P
Sea Urchin
Strong. purpuratus
XP_796888
681
77973
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.5
94.1
N.A.
90.6
30.5
N.A.
88.5
83.3
N.A.
78.9
31.7
46.5
N.A.
29.6
35.5
Protein Similarity:
100
100
99.7
96.3
N.A.
94.3
50
N.A.
93.4
91.1
N.A.
88.5
50.6
65.6
N.A.
48.6
47.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
N.A.
100
6.6
53.3
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
N.A.
100
26.6
66.6
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
62
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% D
% Glu:
0
8
8
0
8
0
16
8
0
0
8
0
77
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
8
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
62
0
0
62
77
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
70
0
0
8
8
% P
% Gln:
0
0
0
62
8
16
0
0
0
0
0
0
8
0
0
% Q
% Arg:
70
0
70
0
0
0
0
0
8
0
0
70
0
0
70
% R
% Ser:
0
8
0
8
0
0
0
62
0
0
0
0
0
70
8
% S
% Thr:
0
0
0
8
62
0
0
16
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _