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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKB All Species: 28.79
Human Site: S231 Identified Species: 52.78
UniProt: Q93100 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93100 NP_000284.1 1093 124884 S231 G S K Y N N G S T E L H S S S
Chimpanzee Pan troglodytes XP_001162360 1093 124839 S231 G S K Y N N G S T E L H S S S
Rhesus Macaque Macaca mulatta XP_001113858 1093 124900 S231 G S K Y N N G S T E L H S S S
Dog Lupus familis XP_863764 1086 123962 S231 S T E L H S S S V G L A K A A
Cat Felis silvestris
Mouse Mus musculus Q7TSH2 1085 123871 S230 S T E L H S S S V G L A K A A
Rat Rattus norvegicus Q64649 1242 139137 C239 L A D E V Q H C Q S I L N T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507442 1100 125727 S238 G S K Y N N G S T E L H S S S
Chicken Gallus gallus NP_001007832 1086 123548 S231 C P E L H S S S V G L A K A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698197 1087 124284 S233 S T E L H S S S V G L A K A A
Tiger Blowfish Takifugu rubipres Q9W6R1 1229 137905 D256 A S P S K E I D A G L L S V I
Fruit Fly Dros. melanogaster Q9VLS1 1093 124845 T232 G S K Y N N G T P E I H A S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34335 1226 139432 T280 D P E L V S Q T R E T I T Q R
Sea Urchin Strong. purpuratus XP_796888 681 77973
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.5 94.1 N.A. 90.6 30.5 N.A. 88.5 83.3 N.A. 78.9 31.7 46.5 N.A. 29.6 35.5
Protein Similarity: 100 100 99.7 96.3 N.A. 94.3 50 N.A. 93.4 91.1 N.A. 88.5 50.6 65.6 N.A. 48.6 47.2
P-Site Identity: 100 100 100 13.3 N.A. 13.3 0 N.A. 100 13.3 N.A. 13.3 20 73.3 N.A. 6.6 0
P-Site Similarity: 100 100 100 53.3 N.A. 53.3 26.6 N.A. 100 46.6 N.A. 53.3 20 93.3 N.A. 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 8 0 0 31 8 31 31 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 39 8 0 8 0 0 0 47 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 0 0 0 0 0 39 0 0 39 0 0 0 0 0 % G
% His: 0 0 0 0 31 0 8 0 0 0 0 39 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 16 8 0 0 8 % I
% Lys: 0 0 39 0 8 0 0 0 0 0 0 0 31 0 0 % K
% Leu: 8 0 0 39 0 0 0 0 0 0 70 16 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 39 39 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 16 8 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 8 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % R
% Ser: 24 47 0 8 0 39 31 62 0 8 0 0 39 39 39 % S
% Thr: 0 24 0 0 0 0 0 16 31 0 8 0 8 8 0 % T
% Val: 0 0 0 0 16 0 0 0 31 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 39 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _