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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DVL3 All Species: 16.06
Human Site: S643 Identified Species: 39.26
UniProt: Q92997 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92997 NP_004414.3 716 78055 S643 S H H S L A S S L R S H H T H
Chimpanzee Pan troglodytes Q5IS48 670 72833 S610 S S P R S Q A S A T A P G L P
Rhesus Macaque Macaca mulatta XP_001094101 740 79711 S667 S H H S L A S S L R S H H T H
Dog Lupus familis XP_535822 716 78058 S643 S H H S M A S S L R S H H T H
Cat Felis silvestris
Mouse Mus musculus Q61062 716 78104 S643 S H H S L T S S L R S H H T H
Rat Rattus norvegicus Q9WVB9 695 75429 R626 R P V S Q L S R G S S P R S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422756 833 90624 H764 L A H S I R S H H S Q Q S Y G
Frog Xenopus laevis Q6DKE2 717 78751 S641 S I A H S I R S H H T H Q S F
Zebra Danio Brachydanio rerio NP_571832 676 73906 V616 A P S E R S G V P P S E G S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P51140 623 68898 K563 S S D V L T S K D I S A S Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.8 90.9 99.3 N.A. 98.7 66.4 N.A. N.A. 75 85.3 69.6 N.A. 42.4 N.A. N.A. N.A.
Protein Similarity: 100 76.8 92.8 99.7 N.A. 99 79.4 N.A. N.A. 80.4 92.3 78 N.A. 56.9 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 20 N.A. N.A. 20 20 6.6 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 93.3 26.6 N.A. N.A. 26.6 33.3 26.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 30 10 0 10 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 10 0 10 0 0 0 20 0 10 % G
% His: 0 40 50 10 0 0 0 10 20 10 0 50 40 0 40 % H
% Ile: 0 10 0 0 10 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 40 10 0 0 40 0 0 0 0 10 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 20 10 0 0 0 0 0 10 10 0 20 0 0 10 % P
% Gln: 0 0 0 0 10 10 0 0 0 0 10 10 10 10 10 % Q
% Arg: 10 0 0 10 10 10 10 10 0 40 0 0 10 0 0 % R
% Ser: 70 20 10 60 20 10 70 60 0 20 70 0 20 30 10 % S
% Thr: 0 0 0 0 0 20 0 0 0 10 10 0 0 40 0 % T
% Val: 0 0 10 10 0 0 0 10 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _