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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DVL3
All Species:
19.7
Human Site:
S140
Identified Species:
48.15
UniProt:
Q92997
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92997
NP_004414.3
716
78055
S140
T
E
T
D
S
L
V
S
A
Q
R
E
R
P
R
Chimpanzee
Pan troglodytes
Q5IS48
670
72833
D132
A
S
S
R
D
G
M
D
N
E
T
G
T
E
S
Rhesus Macaque
Macaca mulatta
XP_001094101
740
79711
S164
T
E
T
D
S
L
V
S
A
Q
R
E
R
P
R
Dog
Lupus familis
XP_535822
716
78058
S140
T
E
T
D
S
L
V
S
A
Q
R
E
R
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61062
716
78104
S140
T
E
T
D
S
L
V
S
A
Q
R
E
R
P
R
Rat
Rattus norvegicus
Q9WVB9
695
75429
H143
G
T
E
S
M
V
S
H
R
R
E
R
A
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422756
833
90624
S263
E
T
D
S
V
V
S
S
Q
R
E
R
P
R
R
Frog
Xenopus laevis
Q6DKE2
717
78751
A140
E
T
D
S
V
V
S
A
R
R
E
R
P
G
R
Zebra Danio
Brachydanio rerio
NP_571832
676
73906
S138
T
E
T
D
S
V
V
S
H
R
R
D
R
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51140
623
68898
S85
C
F
N
G
R
V
V
S
W
L
V
S
A
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.8
90.9
99.3
N.A.
98.7
66.4
N.A.
N.A.
75
85.3
69.6
N.A.
42.4
N.A.
N.A.
N.A.
Protein Similarity:
100
76.8
92.8
99.7
N.A.
99
79.4
N.A.
N.A.
80.4
92.3
78
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
N.A.
13.3
6.6
66.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
N.A.
26.6
26.6
86.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
40
0
0
0
20
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
50
10
0
0
10
0
0
0
10
0
20
0
% D
% Glu:
20
50
10
0
0
0
0
0
0
10
30
40
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
10
0
0
0
0
0
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
40
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
20
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
40
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
20
40
50
30
50
20
80
% R
% Ser:
0
10
10
30
50
0
30
70
0
0
0
10
0
0
10
% S
% Thr:
50
30
50
0
0
0
0
0
0
0
10
0
10
0
0
% T
% Val:
0
0
0
0
20
50
60
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _