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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO1
All Species:
11.21
Human Site:
T40
Identified Species:
20.56
UniProt:
Q92973
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92973
NP_002261.3
898
102355
T40
P
D
T
T
I
Q
R
T
V
Q
Q
K
L
E
Q
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
I203
P
N
T
A
T
Q
R
I
V
Q
D
K
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001095625
862
98044
K36
I
Q
R
T
V
Q
Q
K
L
E
Q
L
N
Q
Y
Dog
Lupus familis
XP_535270
925
104519
S67
N
K
G
R
S
S
P
S
C
K
K
K
L
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFY9
898
102339
T40
P
D
T
T
I
Q
R
T
V
Q
Q
K
L
E
Q
Rat
Rattus norvegicus
XP_001070389
895
101848
T37
P
D
T
T
I
Q
R
T
V
Q
Q
K
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512908
879
99027
N37
A
T
K
L
E
Q
L
N
Q
Y
P
D
F
N
N
Chicken
Gallus gallus
XP_424806
890
101281
K36
T
Q
R
A
V
Q
Q
K
L
E
Q
L
N
Q
Y
Frog
Xenopus laevis
NP_001088603
890
101114
K36
T
Q
R
A
V
Q
Q
K
L
E
Q
L
N
Q
F
Zebra Danio
Brachydanio rerio
XP_691079
891
101212
K36
T
Q
R
S
V
Q
Q
K
L
E
Q
L
N
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
E36
M
A
V
Q
M
K
L
E
E
F
N
R
Y
P
D
Honey Bee
Apis mellifera
XP_392373
933
105655
A66
P
D
T
A
T
Q
R
A
V
Q
E
K
L
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
Q43
A
M
E
N
F
Q
L
Q
P
E
F
L
N
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.2
95.6
93
N.A.
99.6
98.8
N.A.
91.1
95.8
93.6
91.8
N.A.
73.7
75.4
N.A.
N.A.
Protein Similarity:
100
79.2
95.9
94.8
N.A.
99.8
99.3
N.A.
92.8
97.5
96.5
96.3
N.A.
85.1
86.3
N.A.
N.A.
P-Site Identity:
100
60
20
26.6
N.A.
100
100
N.A.
6.6
13.3
13.3
13.3
N.A.
0
66.6
N.A.
N.A.
P-Site Similarity:
100
73.3
53.3
46.6
N.A.
100
100
N.A.
6.6
46.6
46.6
53.3
N.A.
20
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
31
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
31
0
0
0
0
0
0
0
0
8
8
0
0
8
% D
% Glu:
0
0
8
0
8
0
0
8
8
39
8
0
0
39
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
8
0
8
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
24
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
8
0
31
0
8
8
47
0
8
0
% K
% Leu:
0
0
0
8
0
0
24
0
31
0
0
39
47
0
8
% L
% Met:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
8
0
0
0
8
0
0
8
0
39
8
8
% N
% Pro:
39
0
0
0
0
0
8
0
8
0
8
0
0
8
0
% P
% Gln:
0
31
0
8
0
85
31
8
8
39
54
0
0
31
39
% Q
% Arg:
0
0
31
8
0
0
39
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
8
8
8
0
8
0
0
0
0
0
0
0
% S
% Thr:
24
8
39
31
16
0
0
24
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
31
0
0
0
39
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _