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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO1
All Species:
44.24
Human Site:
S173
Identified Species:
81.11
UniProt:
Q92973
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92973
NP_002261.3
898
102355
S173
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
S336
D
S
S
E
L
L
D
S
D
A
L
N
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001095625
862
98044
S165
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Dog
Lupus familis
XP_535270
925
104519
S200
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFY9
898
102339
S173
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Rat
Rattus norvegicus
XP_001070389
895
101848
S170
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512908
879
99027
L164
E
I
L
D
S
D
V
L
D
R
P
L
N
I
M
Chicken
Gallus gallus
XP_424806
890
101281
S165
D
S
A
E
I
L
D
S
D
V
L
D
R
P
L
Frog
Xenopus laevis
NP_001088603
890
101114
S165
D
S
A
E
I
L
D
S
D
V
L
E
R
P
L
Zebra Danio
Brachydanio rerio
XP_691079
891
101212
S165
D
S
A
E
I
L
D
S
D
M
L
E
R
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
S163
D
S
A
E
I
L
D
S
A
A
L
N
R
P
L
Honey Bee
Apis mellifera
XP_392373
933
105655
S199
D
S
S
E
I
L
D
S
D
A
L
N
R
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
L180
D
S
A
Q
F
F
Q
L
E
W
S
G
N
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.2
95.6
93
N.A.
99.6
98.8
N.A.
91.1
95.8
93.6
91.8
N.A.
73.7
75.4
N.A.
N.A.
Protein Similarity:
100
79.2
95.9
94.8
N.A.
99.8
99.3
N.A.
92.8
97.5
96.5
96.3
N.A.
85.1
86.3
N.A.
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
6.6
100
93.3
86.6
N.A.
80
80
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
86.6
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
77
0
0
0
0
0
8
24
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
8
0
8
85
0
85
0
0
47
0
0
0
% D
% Glu:
8
0
0
85
0
0
0
0
8
0
0
16
0
0
0
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
77
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
0
8
85
0
16
0
0
85
8
0
0
85
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
24
16
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
85
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
85
0
0
% R
% Ser:
0
93
16
0
8
0
0
85
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
8
0
0
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _