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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIT1 All Species: 13.64
Human Site: T127 Identified Species: 21.43
UniProt: Q92963 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92963 NP_008843.1 219 25145 T127 R V R R T D D T P V V L V G N
Chimpanzee Pan troglodytes XP_513868 236 27099 T144 R V R R T D D T P V V L V G N
Rhesus Macaque Macaca mulatta XP_001083497 217 24677 I126 Q V R H T Y E I P L V L V G N
Dog Lupus familis XP_537249 219 25045 T127 R V R R T D D T P V V L V G N
Cat Felis silvestris
Mouse Mus musculus P70426 219 25150 T127 R V R R T D D T P V V L V G N
Rat Rattus norvegicus Q5BJQ5 217 24743 I126 Q V R H T Y E I P L V L V G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506896 217 24867 I126 K V R H T Y D I P L V L V G N
Chicken Gallus gallus NP_001026498 162 18298 Q82 E F T A M R D Q Y M R A G E G
Frog Xenopus laevis Q7ZXH7 184 20815 D105 E Q I L R V K D T D D V P M I
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 D105 E Q I L R V K D T D D V P M I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 D105 E Q I L R V K D T D D V P M V
Honey Bee Apis mellifera XP_395139 235 26905 I139 R V R A N E D I P L V L V G N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783565 275 31241 I128 R V R N T E D I P I V L V G N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 E156 L L R S N V D E V F V D L V R
Red Bread Mold Neurospora crassa P22126 213 24008 R126 V G N K Y D L R G E R V V S E
Conservation
Percent
Protein Identity: 100 92.8 66.2 96.8 N.A. 94.9 63.9 N.A. 70.7 69.8 41.5 42.4 N.A. 43.3 50.2 N.A. 48.7
Protein Similarity: 100 92.8 80.8 96.8 N.A. 98.1 81.2 N.A. 83.1 71.2 62 62 N.A. 62.5 64.6 N.A. 59.2
P-Site Identity: 100 100 60 100 N.A. 100 60 N.A. 66.6 6.6 0 0 N.A. 0 66.6 N.A. 73.3
P-Site Similarity: 100 100 80 100 N.A. 100 80 N.A. 80 13.3 6.6 6.6 N.A. 6.6 80 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.5 41.1
Protein Similarity: N.A. N.A. N.A. N.A. 56.2 63.4
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 0 0 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 34 60 20 0 20 20 7 0 0 0 % D
% Glu: 27 0 0 0 0 14 14 7 0 7 0 0 0 7 7 % E
% Phe: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 0 0 7 60 7 % G
% His: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 0 34 0 7 0 0 0 0 14 % I
% Lys: 7 0 0 7 0 0 20 0 0 0 0 0 0 0 0 % K
% Leu: 7 7 0 20 0 0 7 0 0 27 0 60 7 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 7 0 0 0 20 0 % M
% Asn: 0 0 7 7 14 0 0 0 0 0 0 0 0 0 60 % N
% Pro: 0 0 0 0 0 0 0 0 60 0 0 0 20 0 0 % P
% Gln: 14 20 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 40 0 67 27 20 7 0 7 0 0 14 0 0 0 7 % R
% Ser: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % S
% Thr: 0 0 7 0 54 0 0 27 20 0 0 0 0 0 0 % T
% Val: 7 60 0 0 0 27 0 0 7 27 67 27 67 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 20 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _