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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS5
All Species:
44.24
Human Site:
T311
Identified Species:
57.25
UniProt:
Q92905
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92905
NP_006828.2
334
37579
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Chimpanzee
Pan troglodytes
XP_522159
334
37588
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Rhesus Macaque
Macaca mulatta
XP_001097650
268
29954
I246
R
D
S
C
K
T
T
I
E
A
I
H
G
L
M
Dog
Lupus familis
XP_535093
334
37546
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O35864
334
37530
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Rat
Rattus norvegicus
NP_001020866
334
37560
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512862
334
37512
T311
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Chicken
Gallus gallus
NP_001034400
338
37847
T315
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Frog
Xenopus laevis
Q6GLM9
332
37492
T309
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Zebra Danio
Brachydanio rerio
Q6PC30
334
37563
T309
T
R
D
S
C
K
T
T
I
E
A
I
H
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ58
327
37065
T303
T
R
D
C
S
R
S
T
I
E
L
I
H
G
L
Honey Bee
Apis mellifera
XP_623806
344
38683
T314
T
R
D
S
C
K
T
T
I
E
I
I
H
G
L
Nematode Worm
Caenorhab. elegans
P91001
368
40990
R312
G
D
E
L
E
T
G
R
I
S
H
L
V
K
Q
Sea Urchin
Strong. purpuratus
XP_001190460
287
32154
I265
R
D
S
C
K
S
T
I
E
V
I
H
G
L
M
Poplar Tree
Populus trichocarpa
XP_002324396
366
40869
I326
I
T
R
D
S
A
K
I
T
V
E
Q
V
H
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAZ7
357
39713
A315
A
K
I
T
R
D
S
A
K
I
T
V
E
Q
V
Baker's Yeast
Sacchar. cerevisiae
Q12468
440
50793
D341
F
S
G
D
N
T
S
D
V
D
M
E
D
R
N
Red Bread Mold
Neurospora crassa
Q7RXX8
336
37444
A303
L
S
E
V
K
Q
I
A
A
K
E
R
S
G
L
Conservation
Percent
Protein Identity:
100
99.6
80.2
99.6
N.A.
99.4
99
N.A.
99
97.9
96.4
96.1
N.A.
73.6
78.7
50.5
74.8
Protein Similarity:
100
99.6
80.2
100
N.A.
100
99.6
N.A.
100
98.8
98.1
98.1
N.A.
86.2
87.7
65.4
80.8
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
93.3
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
80
93.3
20
13.3
Percent
Protein Identity:
62.8
N.A.
N.A.
63.5
27.2
49.4
Protein Similarity:
74
N.A.
N.A.
75.3
46.1
65.1
P-Site Identity:
0
N.A.
N.A.
0
0
13.3
P-Site Similarity:
0
N.A.
N.A.
33.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
6
0
12
6
6
50
0
0
0
0
% A
% Cys:
0
0
0
17
56
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
62
12
0
6
0
6
0
6
0
0
6
0
0
% D
% Glu:
0
0
12
0
6
0
0
0
12
62
12
6
6
0
0
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
0
6
0
0
0
6
0
0
0
0
0
12
67
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
12
62
6
0
% H
% Ile:
6
0
6
0
0
0
6
17
67
6
17
62
0
0
0
% I
% Lys:
0
6
0
0
17
56
6
0
6
6
0
0
0
6
0
% K
% Leu:
6
0
0
6
0
0
0
0
0
0
6
6
0
12
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
12
% M
% Asn:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
6
0
6
6
% Q
% Arg:
12
62
6
0
6
6
0
6
0
0
0
6
0
6
0
% R
% Ser:
0
12
12
56
12
6
17
0
0
6
0
0
6
0
0
% S
% Thr:
62
6
0
6
0
17
67
62
6
0
6
0
0
0
0
% T
% Val:
0
0
0
6
0
0
0
0
6
12
0
6
12
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _