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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS5
All Species:
43.33
Human Site:
S296
Identified Species:
56.08
UniProt:
Q92905
Number Species:
17
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92905
NP_006828.2
334
37579
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Chimpanzee
Pan troglodytes
XP_522159
334
37588
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Rhesus Macaque
Macaca mulatta
XP_001097650
268
29954
E231
E
T
H
D
R
K
S
E
D
K
L
A
K
A
T
Dog
Lupus familis
XP_535093
334
37546
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
O35864
334
37530
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Rat
Rattus norvegicus
NP_001020866
334
37560
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512862
334
37512
S296
L
E
T
H
D
R
K
S
E
D
K
L
A
K
A
Chicken
Gallus gallus
NP_001034400
338
37847
S300
L
E
T
H
D
K
K
S
E
D
K
L
A
K
A
Frog
Xenopus laevis
Q6GLM9
332
37492
S294
L
E
S
H
D
R
K
S
E
D
K
L
A
K
A
Zebra Danio
Brachydanio rerio
Q6PC30
334
37563
S294
L
D
T
H
D
R
K
S
E
D
K
L
A
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ58
327
37065
S288
T
D
V
N
E
K
R
S
E
D
K
L
S
K
A
Honey Bee
Apis mellifera
XP_623806
344
38683
T299
T
D
P
H
D
R
S
T
V
E
K
L
M
K
A
Nematode Worm
Caenorhab. elegans
P91001
368
40990
V297
G
H
E
A
L
M
K
V
V
T
D
A
K
A
V
Sea Urchin
Strong. purpuratus
XP_001190460
287
32154
E250
V
D
H
E
K
K
A
E
D
K
L
G
K
A
T
Poplar Tree
Populus trichocarpa
XP_002324396
366
40869
D311
M
A
P
Q
R
K
K
D
E
E
S
Q
L
A
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAZ7
357
39713
R300
A
P
A
G
H
Q
R
R
K
E
D
E
P
Q
L
Baker's Yeast
Sacchar. cerevisiae
Q12468
440
50793
E326
T
Q
R
G
D
S
T
E
T
S
S
F
G
S
M
Red Bread Mold
Neurospora crassa
Q7RXX8
336
37444
V288
R
G
P
K
S
D
A
V
D
Q
N
I
E
K
L
Conservation
Percent
Protein Identity:
100
99.6
80.2
99.6
N.A.
99.4
99
N.A.
99
97.9
96.4
96.1
N.A.
73.6
78.7
50.5
74.8
Protein Similarity:
100
99.6
80.2
100
N.A.
100
99.6
N.A.
100
98.8
98.1
98.1
N.A.
86.2
87.7
65.4
80.8
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
46.6
46.6
6.6
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
66.6
6.6
26.6
Percent
Protein Identity:
62.8
N.A.
N.A.
63.5
27.2
49.4
Protein Similarity:
74
N.A.
N.A.
75.3
46.1
65.1
P-Site Identity:
13.3
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
33.3
N.A.
N.A.
33.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
6
0
0
12
0
0
0
0
12
50
23
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
0
6
62
6
0
6
17
56
12
0
0
0
0
% D
% Glu:
6
45
6
6
6
0
0
17
62
17
0
6
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% F
% Gly:
6
6
0
12
0
0
0
0
0
0
0
6
6
0
0
% G
% His:
0
6
12
56
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% I
% Lys:
0
0
0
6
6
28
62
0
6
12
62
0
17
67
6
% K
% Leu:
50
0
0
0
6
0
0
0
0
0
12
62
6
0
12
% L
% Met:
6
0
0
0
0
6
0
0
0
0
0
0
6
0
6
% M
% Asn:
0
0
0
6
0
0
0
0
0
0
6
0
0
0
0
% N
% Pro:
0
6
17
0
0
0
0
0
0
0
0
0
6
0
0
% P
% Gln:
0
6
0
6
0
6
0
0
0
6
0
6
0
6
0
% Q
% Arg:
6
0
6
0
12
50
12
6
0
0
0
0
0
0
0
% R
% Ser:
0
0
6
0
6
6
12
56
0
6
12
0
6
6
0
% S
% Thr:
17
6
45
0
0
0
6
6
6
6
0
0
0
0
12
% T
% Val:
6
0
6
0
0
0
0
12
12
0
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _