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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS5
All Species:
44.55
Human Site:
S270
Identified Species:
57.65
UniProt:
Q92905
Number Species:
17
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92905
NP_006828.2
334
37579
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Chimpanzee
Pan troglodytes
XP_522159
334
37588
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Rhesus Macaque
Macaca mulatta
XP_001097650
268
29954
E205
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
A
Dog
Lupus familis
XP_535093
334
37546
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Cat
Felis silvestris
Mouse
Mus musculus
O35864
334
37530
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Rat
Rattus norvegicus
NP_001020866
334
37560
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512862
334
37512
S270
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Chicken
Gallus gallus
NP_001034400
338
37847
S274
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Frog
Xenopus laevis
Q6GLM9
332
37492
S268
T
G
Q
V
F
D
L
S
E
K
L
E
Q
S
E
Zebra Danio
Brachydanio rerio
Q6PC30
334
37563
S268
T
G
Q
V
F
D
L
S
E
K
L
E
Q
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZ58
327
37065
Q262
N
T
E
Y
T
T
G
Q
I
M
D
L
S
E
K
Honey Bee
Apis mellifera
XP_623806
344
38683
S273
T
G
Q
I
F
D
L
S
D
K
L
E
Q
S
E
Nematode Worm
Caenorhab. elegans
P91001
368
40990
N271
N
N
Q
I
Q
D
I
N
Q
K
L
S
A
V
D
Sea Urchin
Strong. purpuratus
XP_001190460
287
32154
S224
I
G
Q
V
S
D
L
S
E
K
L
E
N
A
E
Poplar Tree
Populus trichocarpa
XP_002324396
366
40869
A285
A
G
Q
I
S
D
L
A
E
K
L
E
H
A
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAZ7
357
39713
A274
A
G
Q
I
S
D
L
A
E
K
L
E
Q
A
E
Baker's Yeast
Sacchar. cerevisiae
Q12468
440
50793
N300
S
E
R
V
S
N
E
N
K
K
N
I
D
Y
Q
Red Bread Mold
Neurospora crassa
Q7RXX8
336
37444
G262
S
S
Q
M
V
D
L
G
S
R
I
S
K
A
S
Conservation
Percent
Protein Identity:
100
99.6
80.2
99.6
N.A.
99.4
99
N.A.
99
97.9
96.4
96.1
N.A.
73.6
78.7
50.5
74.8
Protein Similarity:
100
99.6
80.2
100
N.A.
100
99.6
N.A.
100
98.8
98.1
98.1
N.A.
86.2
87.7
65.4
80.8
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
0
86.6
26.6
73.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
100
60
80
Percent
Protein Identity:
62.8
N.A.
N.A.
63.5
27.2
49.4
Protein Similarity:
74
N.A.
N.A.
75.3
46.1
65.1
P-Site Identity:
60
N.A.
N.A.
66.6
13.3
20
P-Site Similarity:
80
N.A.
N.A.
86.6
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
12
0
0
0
0
6
28
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
84
0
0
6
0
6
0
6
0
6
% D
% Glu:
0
6
6
0
0
0
6
6
67
0
6
73
0
12
73
% E
% Phe:
0
0
0
6
56
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
73
0
0
0
0
6
6
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
6
0
0
23
0
0
6
0
6
0
6
6
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
84
0
0
6
0
6
% K
% Leu:
0
0
0
0
0
6
78
0
0
6
78
6
0
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
12
6
0
0
0
6
0
12
0
0
6
0
6
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
84
0
6
0
0
6
6
0
0
6
62
0
6
% Q
% Arg:
0
0
6
0
0
0
0
0
0
6
0
0
0
0
0
% R
% Ser:
12
6
0
0
23
0
6
62
6
0
0
12
12
50
6
% S
% Thr:
56
6
0
0
6
6
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
6
62
6
0
0
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _