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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APBB2
All Species:
14.85
Human Site:
S190
Identified Species:
32.67
UniProt:
Q92870
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92870
NP_775098.2
758
83346
S190
H
G
T
A
E
E
K
S
Q
P
V
Q
G
Q
A
Chimpanzee
Pan troglodytes
XP_001146547
758
83385
S190
H
G
T
A
E
E
K
S
Q
P
V
Q
G
Q
A
Rhesus Macaque
Macaca mulatta
XP_001097537
761
83630
S193
H
G
I
A
E
E
K
S
Q
P
G
Q
G
Q
A
Dog
Lupus familis
XP_851058
758
83089
S190
H
G
V
V
E
E
K
S
Q
P
G
Q
G
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR4
760
83182
A190
Q
G
V
G
E
E
K
A
Q
P
G
P
G
Q
A
Rat
Rattus norvegicus
P46933
711
77638
D161
A
G
E
V
E
E
E
D
E
D
E
E
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507097
616
68316
T66
S
Q
P
G
P
P
A
T
A
M
V
P
T
D
K
Chicken
Gallus gallus
XP_420735
740
81441
D176
S
F
L
N
Y
Y
A
D
L
E
T
S
A
R
E
Frog
Xenopus laevis
NP_001087003
610
66956
A60
N
D
N
Q
S
K
E
A
K
H
H
E
I
C
A
Zebra Danio
Brachydanio rerio
XP_693392
869
95380
P291
I
V
S
D
K
K
S
P
E
H
L
K
T
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787988
848
93773
S189
E
A
L
T
K
Q
R
S
E
Q
I
E
D
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
94.5
N.A.
93.9
46.3
N.A.
63.9
86.2
39.8
58.4
N.A.
N.A.
N.A.
N.A.
30.1
Protein Similarity:
100
99.8
98.2
96.5
N.A.
96
62.2
N.A.
70.4
90.9
53.9
68.4
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
100
86.6
80
N.A.
60
20
N.A.
6.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
80
N.A.
66.6
46.6
N.A.
13.3
6.6
46.6
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
28
0
0
19
19
10
0
0
0
10
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
10
0
0
0
19
0
10
0
0
10
19
10
% D
% Glu:
10
0
10
0
55
55
19
0
28
10
10
28
10
10
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
55
0
19
0
0
0
0
0
0
28
0
46
0
0
% G
% His:
37
0
0
0
0
0
0
0
0
19
10
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
19
19
46
0
10
0
0
10
0
10
10
% K
% Leu:
0
0
19
0
0
0
0
0
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
10
0
10
0
46
0
19
0
0
0
% P
% Gln:
10
10
0
10
0
10
0
0
46
10
0
37
0
46
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
19
0
10
0
10
0
10
46
0
0
0
10
0
0
10
% S
% Thr:
0
0
19
10
0
0
0
10
0
0
10
0
19
0
10
% T
% Val:
0
10
19
19
0
0
0
0
0
0
28
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _