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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEO1 All Species: 26.67
Human Site: S1272 Identified Species: 48.89
UniProt: Q92859 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92859 NP_002490.2 1461 160017 S1272 F H S S S L A S P A R S H L Y
Chimpanzee Pan troglodytes XP_510660 1613 175322 S1424 F H S S S L A S P A R S H L Y
Rhesus Macaque Macaca mulatta XP_001093533 1612 176214 S1423 F H S S S L A S P A R S H L Y
Dog Lupus familis XP_544760 1466 160256 S1277 F H S S S L A S P A R S H L Y
Cat Felis silvestris
Mouse Mus musculus P97798 1493 163142 S1303 F H S S S L A S P A R S H L Y
Rat Rattus norvegicus P97603 1377 150619 D1191 Y R G H E S E D S M S T L A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507960 1433 157168 S1245 F H S S S L A S P T R S Y L H
Chicken Gallus gallus Q90610 1443 158032 S1257 F H S G S L A S P T R S Y L H
Frog Xenopus laevis NP_001079254 1427 156515 P1235 P P V V S A I P V P T L E S A
Zebra Danio Brachydanio rerio Q2EY14 1149 126278 C963 R S K T R K S C T T K S I R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725185 1375 151646 Y1189 N S L D K R S Y V P G Y M T T
Honey Bee Apis mellifera XP_001122444 1492 165549 P1305 P S A R Q N Y P R T V A Q Y S
Nematode Worm Caenorhab. elegans NP_491664 1415 154419 H1220 V Y T G T G R H Q P I Q R I D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 87.8 95.9 N.A. 91.9 88.9 N.A. 88 85.6 50.7 25.7 N.A. 33.7 34.3 28.5 N.A.
Protein Similarity: 100 90.4 88.4 97.5 N.A. 94.1 91.5 N.A. 92.2 90.8 69.8 40.9 N.A. 52 53.6 47.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 80 73.3 6.6 6.6 N.A. 0 0 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 93.3 86.6 6.6 26.6 N.A. 6.6 13.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 54 0 0 39 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 8 0 0 0 0 0 8 0 0 % E
% Phe: 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 16 0 8 0 0 0 0 8 0 0 0 8 % G
% His: 0 54 0 8 0 0 0 8 0 0 0 0 39 0 16 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 8 0 8 8 0 % I
% Lys: 0 0 8 0 8 8 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 8 0 0 54 0 0 0 0 0 8 8 54 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 8 0 0 0 0 0 16 54 24 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 0 8 8 0 8 % Q
% Arg: 8 8 0 8 8 8 8 0 8 0 54 0 8 8 0 % R
% Ser: 0 24 54 47 62 8 16 54 8 0 8 62 0 8 8 % S
% Thr: 0 0 8 8 8 0 0 0 8 31 8 8 0 8 8 % T
% Val: 8 0 8 8 0 0 0 0 16 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 8 8 0 0 0 8 16 8 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _