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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TANK
All Species:
18.79
Human Site:
S123
Identified Species:
45.93
UniProt:
Q92844
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92844
NP_004171.2
425
47816
S123
S
S
P
R
K
E
T
S
A
R
S
L
G
S
P
Chimpanzee
Pan troglodytes
XP_001149990
451
50577
S149
S
S
P
R
K
E
T
S
A
R
S
L
G
S
P
Rhesus Macaque
Macaca mulatta
XP_001095739
425
47738
S123
S
S
P
R
K
E
T
S
A
R
S
L
G
S
P
Dog
Lupus familis
XP_850089
426
48187
S123
S
S
P
R
K
E
T
S
P
R
S
L
G
I
P
Cat
Felis silvestris
Mouse
Mus musculus
P70347
448
50921
K158
S
S
G
K
E
S
A
K
G
L
N
I
P
L
H
Rat
Rattus norvegicus
NP_001157545
413
46829
K123
S
S
G
K
E
T
S
K
D
L
S
I
P
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511169
428
48671
S124
S
S
P
R
Q
E
V
S
P
G
V
P
N
V
L
Chicken
Gallus gallus
XP_422036
482
55085
S181
V
P
D
K
P
E
L
S
I
G
I
S
G
I
S
Frog
Xenopus laevis
NP_001089099
484
54702
S132
K
L
R
K
L
E
E
S
Q
K
A
F
E
S
F
Zebra Danio
Brachydanio rerio
NP_001070068
348
39309
Y78
G
E
V
C
E
P
A
Y
R
K
Q
E
A
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
97.1
86.8
N.A.
76.1
79.2
N.A.
65.4
45.8
28.3
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.2
99
90.1
N.A.
82.1
87
N.A.
78
60.7
44.6
42.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
13.3
20
N.A.
40
20
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
40
46.6
N.A.
46.6
26.6
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
0
30
0
10
0
10
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
30
70
10
0
0
0
0
10
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
10
0
20
0
0
0
0
0
10
20
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
20
0
20
0
% I
% Lys:
10
0
0
40
40
0
0
20
0
20
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
0
20
0
40
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
10
50
0
10
10
0
0
20
0
0
10
20
0
40
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
10
50
0
0
0
0
10
40
0
0
0
0
0
% R
% Ser:
70
70
0
0
0
10
10
70
0
0
50
10
0
40
10
% S
% Thr:
0
0
0
0
0
10
40
0
0
0
0
0
0
0
0
% T
% Val:
10
0
10
0
0
0
10
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _