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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREBBP All Species: 39.39
Human Site: T2073 Identified Species: 72.22
UniProt: Q92793 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92793 NP_001073315.1 2442 265351 T2073 A L Q D L L R T L K S P S S P
Chimpanzee Pan troglodytes XP_523285 2442 265358 T2073 A L Q D L L R T L K S P S S P
Rhesus Macaque Macaca mulatta XP_001095225 2442 265320 T2073 A L Q D L L R T L K S P S S P
Dog Lupus familis XP_851777 2404 260682 T2039 A L Q D L L R T L K S P S S P
Cat Felis silvestris
Mouse Mus musculus P45481 2441 265456 T2074 A L Q D L L R T L K S P S S P
Rat Rattus norvegicus NP_596872 2444 265618 T2074 A L Q D L L R T L K S P S S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414964 2447 266615 T2081 A L Q D L L R T L K S P S S P
Frog Xenopus laevis NP_001088637 2428 264402 T2076 A L Q D L L R T L K S P S S P
Zebra Danio Brachydanio rerio NP_001082924 2111 234059 I1815 P Q Q P Q Q G I H A A Q P A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524642 3276 340709 V2738 G M R Q P T H V M Q T N L I P
Honey Bee Apis mellifera XP_001122031 2606 284119 T2277 V L Q Q L M Q T L K N P H T P
Nematode Worm Caenorhab. elegans P34545 2056 227161 N1760 N Q S R Y M P N G P G L G Q S
Sea Urchin Strong. purpuratus XP_782558 2635 288594 T2289 A L Q Q L L Q T L K S P H S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.4 93.9 N.A. 94.8 95.8 N.A. N.A. 88 76 61.5 N.A. 36.5 42.7 30.5 38.5
Protein Similarity: 100 99.9 99.6 95.5 N.A. 96.4 97.2 N.A. N.A. 92 83.3 68.8 N.A. 46.7 54.7 43.9 50.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 6.6 N.A. 6.6 53.3 0 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 20 N.A. 40 80 6.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 70 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 8 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 8 0 0 0 16 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 % K
% Leu: 0 77 0 0 77 70 0 0 77 0 0 8 8 0 0 % L
% Met: 0 8 0 0 0 16 0 0 8 0 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 8 8 0 0 0 % N
% Pro: 8 0 0 8 8 0 8 0 0 8 0 77 8 0 85 % P
% Gln: 0 16 85 24 8 8 16 0 0 8 0 8 0 8 0 % Q
% Arg: 0 0 8 8 0 0 62 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 0 0 0 0 70 0 62 70 8 % S
% Thr: 0 0 0 0 0 8 0 77 0 0 8 0 0 8 0 % T
% Val: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _