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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
19.7
Human Site:
S841
Identified Species:
36.11
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S841
N
M
L
G
P
Q
A
S
Q
L
P
C
P
P
V
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S841
N
M
L
G
P
Q
A
S
Q
L
P
C
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S841
N
M
L
G
P
Q
A
S
Q
L
P
C
P
P
V
Dog
Lupus familis
XP_851777
2404
260682
S806
N
M
L
G
P
Q
A
S
Q
L
P
C
P
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
A842
L
N
M
L
A
P
Q
A
S
Q
L
P
C
P
P
Rat
Rattus norvegicus
NP_596872
2444
265618
T842
L
N
M
L
A
P
Q
T
S
Q
L
P
C
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
S841
M
N
M
L
G
P
Q
S
G
Q
L
C
P
P
V
Frog
Xenopus laevis
NP_001088637
2428
264402
S839
N
M
L
G
P
Q
T
S
Q
L
Q
R
P
A
L
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
E706
E
A
K
Q
E
P
M
E
T
E
D
K
K
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
Q1371
S
V
S
S
L
M
Q
Q
P
L
S
N
R
P
G
Honey Bee
Apis mellifera
XP_001122031
2606
284119
G1041
Q
A
P
S
P
F
S
G
M
Q
Q
Q
S
N
Q
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
N651
K
E
M
F
E
S
A
N
D
R
E
E
Y
Y
H
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
N1034
V
Q
V
P
T
T
V
N
T
Q
Q
K
P
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
N.A.
33.3
66.6
0
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
N.A.
40
73.3
0
N.A.
26.6
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
16
0
39
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
39
16
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% D
% Glu:
8
8
0
0
16
0
0
8
0
8
8
8
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
39
8
0
0
8
8
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
0
16
8
0
0
% K
% Leu:
16
0
39
24
8
0
0
0
0
47
24
0
0
0
8
% L
% Met:
8
39
31
0
0
8
8
0
8
0
0
0
0
0
0
% M
% Asn:
39
24
0
0
0
0
0
16
0
0
0
8
0
8
0
% N
% Pro:
0
0
8
8
47
31
0
0
8
0
31
16
54
62
16
% P
% Gln:
8
8
0
8
0
39
31
8
39
39
24
8
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% R
% Ser:
8
0
8
16
0
8
8
47
16
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
8
8
8
8
16
0
0
0
0
8
0
% T
% Val:
8
8
8
0
0
0
8
0
0
0
0
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _