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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
14.55
Human Site:
S193
Identified Species:
24.62
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S193
R
E
N
L
L
R
L
S
R
E
M
L
E
T
G
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S193
T
E
N
L
L
R
L
S
R
E
M
L
E
T
G
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S174
T
E
N
L
L
R
L
S
R
E
M
L
E
T
G
Dog
Lupus familis
XP_543872
907
102087
S174
M
E
R
L
L
R
L
S
R
E
M
L
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
Y175
E
H
L
V
L
A
E
Y
E
S
D
E
E
R
R
Rat
Rattus norvegicus
XP_001070646
845
94905
S164
K
R
S
I
Y
Y
C
S
R
T
H
S
Q
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
L191
E
D
D
E
T
E
R
L
L
R
L
S
K
E
M
Chicken
Gallus gallus
XP_416375
940
105739
K207
K
R
L
L
Q
L
S
K
E
I
L
S
E
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
E182
A
E
Y
E
S
D
D
E
A
T
P
K
S
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
L161
L
E
E
L
E
K
D
L
D
P
E
S
D
S
D
Honey Bee
Apis mellifera
XP_001121183
769
88327
E124
M
E
Y
L
E
N
F
E
D
E
D
K
E
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
R135
K
V
V
T
L
G
S
R
Q
N
L
C
I
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
R187
S
K
S
T
R
G
G
R
I
S
D
K
D
Y
K
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
E281
T
A
S
D
E
D
K
E
F
L
I
G
D
W
R
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
93.3
93.3
73.3
N.A.
13.3
13.3
N.A.
0
13.3
N.A.
6.6
N.A.
13.3
26.6
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
20
40
N.A.
26.6
26.6
N.A.
6.6
N.A.
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
0
8
0
0
0
8
8
15
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
8
0
15
15
0
15
0
22
0
22
0
8
% D
% Glu:
15
50
8
15
22
8
8
22
15
36
8
8
43
15
8
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
8
0
0
0
0
8
0
8
29
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
8
8
0
8
0
0
% I
% Lys:
22
8
0
0
0
8
8
8
0
0
0
22
8
0
8
% K
% Leu:
8
0
15
50
43
8
29
15
8
8
22
29
0
8
8
% L
% Met:
15
0
0
0
0
0
0
0
0
0
29
0
0
0
8
% M
% Asn:
0
0
22
0
0
8
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
15
8
0
8
29
8
15
36
8
0
0
0
15
15
% R
% Ser:
8
0
22
0
8
0
15
36
0
15
0
29
8
8
0
% S
% Thr:
22
0
0
15
8
0
0
0
0
15
0
0
0
22
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
15
0
8
8
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _