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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC2
All Species:
15.45
Human Site:
Y88
Identified Species:
24.29
UniProt:
Q92769
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92769
NP_001518.2
488
55364
Y88
R
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
Chimpanzee
Pan troglodytes
XP_518700
581
65611
Y181
R
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532270
481
54585
V90
K
Q
M
Q
R
F
N
V
G
E
D
C
P
V
F
Cat
Felis silvestris
Mouse
Mus musculus
P70288
488
55284
Y88
R
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
Rat
Rattus norvegicus
Q4QQW4
482
55074
S88
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521848
455
51607
Q89
S
E
Y
S
K
Q
M
Q
R
F
N
V
G
E
D
Chicken
Gallus gallus
P56519
488
55134
Y88
R
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
Frog
Xenopus laevis
O42227
480
54874
S88
P
D
N
M
S
E
Y
S
K
Q
M
Q
R
F
N
Zebra Danio
Brachydanio rerio
Q803C3
428
48962
N76
F
L
Q
K
V
S
P
N
N
M
Q
G
F
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94517
521
58312
Q90
S
E
Y
N
K
Q
M
Q
R
F
N
V
G
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17695
461
52119
F91
N
P
D
N
L
K
S
F
N
K
Q
M
L
K
F
Sea Urchin
Strong. purpuratus
P56518
576
64060
Q89
N
M
S
E
Y
T
K
Q
M
Q
R
F
N
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56521
513
57528
Q101
T
P
E
T
Q
Q
D
Q
I
R
L
L
K
R
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FML2
471
52633
P97
S
P
E
S
M
G
D
P
S
A
A
R
N
L
R
Baker's Yeast
Sacchar. cerevisiae
P32561
433
48886
E81
M
C
Q
F
H
T
D
E
Y
I
D
F
L
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
96.5
N.A.
99.3
85.8
N.A.
90.7
98.1
87.6
52.6
N.A.
73.3
N.A.
58.8
69.1
Protein Similarity:
100
83.9
N.A.
97.3
N.A.
99.3
93.6
N.A.
91.1
98.1
94.4
70.6
N.A.
81.9
N.A.
76
78.4
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
0
N.A.
0
100
0
13.3
N.A.
6.6
N.A.
46.6
0
P-Site Similarity:
100
100
N.A.
20
N.A.
100
20
N.A.
13.3
100
20
26.6
N.A.
13.3
N.A.
73.3
26.6
Percent
Protein Identity:
N.A.
53.6
N.A.
56.3
53.8
N.A.
Protein Similarity:
N.A.
70.5
N.A.
72.3
69.4
N.A.
P-Site Identity:
N.A.
20
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
14
34
0
0
0
20
0
0
0
14
0
0
0
14
% D
% Glu:
0
14
14
7
0
14
27
7
0
7
0
0
0
14
0
% E
% Phe:
7
0
0
7
0
7
0
7
0
14
0
14
7
14
47
% F
% Gly:
0
0
0
0
0
7
0
0
7
0
0
7
14
0
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
7
0
0
7
14
7
7
0
14
34
0
0
7
7
7
% K
% Leu:
0
7
0
0
7
0
0
0
0
0
7
7
14
7
0
% L
% Met:
7
7
7
14
34
0
14
0
7
7
14
34
0
0
0
% M
% Asn:
14
0
14
40
0
0
7
7
14
0
14
0
14
0
14
% N
% Pro:
14
47
0
0
0
0
7
7
0
0
0
0
7
0
0
% P
% Gln:
0
7
14
7
7
20
0
27
0
20
40
14
27
0
0
% Q
% Arg:
27
0
0
0
7
0
0
0
14
7
7
7
14
34
14
% R
% Ser:
20
0
7
14
14
34
7
14
34
0
0
0
0
7
0
% S
% Thr:
7
0
0
7
0
14
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
7
0
0
7
0
0
0
14
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
7
0
14
27
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _