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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC2
All Species:
22.73
Human Site:
T39
Identified Species:
35.71
UniProt:
Q92769
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92769
NP_001518.2
488
55364
T39
K
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
Chimpanzee
Pan troglodytes
XP_518700
581
65611
T132
K
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532270
481
54585
L41
N
L
L
L
N
Y
G
L
Y
R
K
M
E
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
P70288
488
55284
T39
K
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
Rat
Rattus norvegicus
Q4QQW4
482
55074
H39
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521848
455
51607
L40
R
M
T
H
N
L
L
L
N
Y
G
L
Y
R
K
Chicken
Gallus gallus
P56519
488
55134
T39
K
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
Frog
Xenopus laevis
O42227
480
54874
H39
P
H
R
I
R
M
T
H
N
L
L
L
N
Y
G
Zebra Danio
Brachydanio rerio
Q803C3
428
48962
H27
A
G
H
P
M
K
P
H
R
L
S
L
T
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94517
521
58312
L41
R
M
T
H
N
L
L
L
N
Y
G
L
Y
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17695
461
52119
T42
K
P
H
R
I
R
M
T
H
H
L
V
L
N
Y
Sea Urchin
Strong. purpuratus
P56518
576
64060
L40
R
I
R
M
T
H
N
L
I
L
N
Y
G
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56521
513
57528
T52
K
P
H
R
I
R
M
T
H
S
L
L
A
R
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FML2
471
52633
A48
K
P
H
R
I
R
M
A
H
S
L
I
I
H
Y
Baker's Yeast
Sacchar. cerevisiae
P32561
433
48886
Y32
Y
D
A
D
V
G
N
Y
A
Y
G
A
G
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
N.A.
96.5
N.A.
99.3
85.8
N.A.
90.7
98.1
87.6
52.6
N.A.
73.3
N.A.
58.8
69.1
Protein Similarity:
100
83.9
N.A.
97.3
N.A.
99.3
93.6
N.A.
91.1
98.1
94.4
70.6
N.A.
81.9
N.A.
76
78.4
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
13.3
N.A.
6.6
100
13.3
13.3
N.A.
6.6
N.A.
86.6
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
100
20
N.A.
26.6
100
20
33.3
N.A.
26.6
N.A.
100
13.3
Percent
Protein Identity:
N.A.
53.6
N.A.
56.3
53.8
N.A.
Protein Similarity:
N.A.
70.5
N.A.
72.3
69.4
N.A.
P-Site Identity:
N.A.
80
N.A.
66.6
0
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
93.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
7
7
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
7
0
0
0
20
0
14
0
14
% G
% His:
0
14
54
14
0
7
0
20
47
7
0
0
0
20
0
% H
% Ile:
0
7
0
14
47
0
0
0
7
0
0
7
7
7
0
% I
% Lys:
47
0
0
0
0
7
0
0
0
0
7
0
0
0
14
% K
% Leu:
0
7
7
7
0
14
14
27
0
27
60
67
34
7
0
% L
% Met:
0
14
0
7
7
14
47
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
20
0
14
0
27
27
7
0
14
34
0
% N
% Pro:
14
47
0
7
0
0
7
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
20
47
14
47
0
0
7
7
0
0
0
20
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
14
7
0
0
0
7
% S
% Thr:
0
0
14
0
7
0
14
40
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
0
7
7
20
0
7
14
14
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _