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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGK All Species: 27.88
Human Site: S146 Identified Species: 51.11
UniProt: Q92643 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92643 NP_005473.1 395 45252 S146 I P P S T P R S K R L L S D D
Chimpanzee Pan troglodytes XP_001168438 395 45203 S146 I P P S T P R S K R L L S D D
Rhesus Macaque Macaca mulatta XP_001102474 395 45245 S146 I P P S T P R S K R L L S D D
Dog Lupus familis XP_853775 396 45507 S147 I P S S T P R S K R L L S D D
Cat Felis silvestris
Mouse Mus musculus Q9CXY9 395 44877 S146 V P P S T P R S K R L L S D D
Rat Rattus norvegicus Q9R0J8 435 49448 H164 V F P N E D L H V K D L N K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002149 389 44519 S143 L P L S T P R S K R L L S D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T4E1 355 40350 L135 T V E N F V R L L T G R T Q N
Honey Bee Apis mellifera XP_394531 425 49004 S143 K L L T D E G S N I L I Y L T
Nematode Worm Caenorhab. elegans P49048 319 36399 R99 P G T V Y A A R A G T N L Y G
Sea Urchin Strong. purpuratus XP_785235 391 44152 S144 L P P S T P R S K R L L T D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49047 478 52652 G144 T A L K G G S G K V V D S G P
Baker's Yeast Sacchar. cerevisiae P49018 411 47384 R141 E D H P K S K R L L T D E N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.4 93.4 N.A. 91.3 26.2 N.A. N.A. N.A. N.A. 78.9 N.A. 51.3 53.4 44.8 58.7
Protein Similarity: 100 99.7 97.7 94.9 N.A. 93.6 44.1 N.A. N.A. N.A. N.A. 87 N.A. 67.5 68.2 59.4 74.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. N.A. N.A. N.A. 86.6 N.A. 6.6 13.3 0 86.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 40 N.A. N.A. N.A. N.A. 93.3 N.A. 26.6 26.6 0 100
Percent
Protein Identity: N.A. N.A. N.A. 23.6 44.5 N.A.
Protein Similarity: N.A. N.A. N.A. 41.4 63.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 8 0 0 0 0 8 16 0 54 54 % D
% Glu: 8 0 8 0 8 8 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 8 8 8 8 0 8 8 0 0 8 8 % G
% His: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 31 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % I
% Lys: 8 0 0 8 8 0 8 0 62 8 0 0 0 8 0 % K
% Leu: 16 8 24 0 0 0 8 8 16 8 62 62 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 16 0 0 0 0 8 0 0 8 8 8 8 % N
% Pro: 8 54 47 8 0 54 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 62 16 0 54 0 8 0 0 0 % R
% Ser: 0 0 8 54 0 8 8 62 0 0 0 0 54 0 8 % S
% Thr: 16 0 8 8 54 0 0 0 0 8 16 0 16 0 16 % T
% Val: 16 8 0 8 0 8 0 0 8 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _