KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXDN
All Species:
16.06
Human Site:
T249
Identified Species:
29.44
UniProt:
Q92626
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92626
NP_036425.1
1479
165275
T249
N
C
E
R
P
R
I
T
S
E
P
Q
D
A
D
Chimpanzee
Pan troglodytes
XP_001169397
866
97623
Rhesus Macaque
Macaca mulatta
XP_001108296
1316
146985
P162
N
N
K
L
S
K
I
P
A
G
S
F
S
N
L
Dog
Lupus familis
XP_544073
1296
144318
E141
M
A
R
N
S
A
G
E
V
K
T
Q
N
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQ28
1475
165115
T246
N
C
E
R
P
R
I
T
S
E
P
Q
D
A
D
Rat
Rattus norvegicus
XP_002726775
1475
165020
T246
N
C
E
R
P
R
I
T
S
E
P
Q
D
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514779
1469
164647
T237
N
C
E
S
P
R
I
T
F
E
P
R
D
V
E
Chicken
Gallus gallus
XP_419931
1456
163977
D230
R
I
T
S
E
P
Q
D
V
D
V
T
S
G
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665312
1530
170912
T232
G
A
E
V
P
R
I
T
S
E
P
Q
D
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ4
1527
170496
L239
K
C
A
K
P
Q
F
L
V
A
P
Q
D
A
Q
Honey Bee
Apis mellifera
XP_396476
1293
147180
N139
E
Q
L
Y
L
H
Y
N
H
L
R
E
I
K
K
Nematode Worm
Caenorhab. elegans
Q1ENI8
1285
146318
K131
P
L
A
S
L
N
L
K
R
N
H
I
Q
F
I
Sea Urchin
Strong. purpuratus
XP_797821
1402
156847
V229
A
P
K
R
P
H
F
V
V
E
P
H
N
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.4
56
55.8
N.A.
91
89.7
N.A.
65.4
83.4
N.A.
67.8
N.A.
41.5
40.7
36.1
46.5
Protein Similarity:
100
58.4
68.4
66.8
N.A.
94.6
93.2
N.A.
78.5
89.7
N.A.
80.3
N.A.
57.8
56.7
51
60.6
P-Site Identity:
100
0
13.3
13.3
N.A.
100
100
N.A.
66.6
0
N.A.
73.3
N.A.
40
0
0
33.3
P-Site Similarity:
100
0
33.3
26.6
N.A.
100
100
N.A.
80
13.3
N.A.
73.3
N.A.
53.3
6.6
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
0
0
8
0
0
8
8
0
0
0
39
0
% A
% Cys:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
8
0
0
47
0
39
% D
% Glu:
8
0
39
0
8
0
0
8
0
47
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
16
0
8
0
0
8
0
8
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
16
0
0
8
0
8
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
47
0
0
0
0
8
8
0
8
% I
% Lys:
8
0
16
8
0
8
0
8
0
8
0
0
0
8
8
% K
% Leu:
0
8
8
8
16
0
8
8
0
8
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
39
8
0
8
0
8
0
8
0
8
0
0
16
8
8
% N
% Pro:
8
8
0
0
54
8
0
8
0
0
54
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
8
0
0
0
0
47
8
0
8
% Q
% Arg:
8
0
8
31
0
39
0
0
8
0
8
8
0
0
0
% R
% Ser:
0
0
0
24
16
0
0
0
31
0
8
0
16
0
0
% S
% Thr:
0
0
8
0
0
0
0
39
0
0
8
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
8
31
0
8
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _