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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDN All Species: 4.24
Human Site: T1401 Identified Species: 7.78
UniProt: Q92626 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92626 NP_036425.1 1479 165275 T1401 K T I T D L R T Q I K K L E S
Chimpanzee Pan troglodytes XP_001169397 866 97623 A805 S T T E C V D A G G E S H A N
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 R1255 L K Q A S L G R V L C D N G D
Dog Lupus familis XP_544073 1296 144318 I1234 G C T D D K G I R R K D N E H
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 K1397 K I I T D L R K Q I N S L E S
Rat Rattus norvegicus XP_002726775 1475 165020 K1397 K I I T D L R K Q I N S L E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 Q1387 E T I T A L R Q Q I N K L E A
Chicken Gallus gallus XP_419931 1456 163977 S1377 K T I S S L R S Q I K K L E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 K1454 K T I T S L R K Q I K R L E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 A1451 A Q V V Q L A A A P P Q L V S
Honey Bee Apis mellifera XP_396476 1293 147180 Q1232 A T K Y L P S Q N I F N L K N
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 L1224 D N V C P T M L D R I L R S R
Sea Urchin Strong. purpuratus XP_797821 1402 156847 V1341 P S R R Q K F V E V E I D A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.4 56 55.8 N.A. 91 89.7 N.A. 65.4 83.4 N.A. 67.8 N.A. 41.5 40.7 36.1 46.5
Protein Similarity: 100 58.4 68.4 66.8 N.A. 94.6 93.2 N.A. 78.5 89.7 N.A. 80.3 N.A. 57.8 56.7 51 60.6
P-Site Identity: 100 6.6 6.6 20 N.A. 73.3 73.3 N.A. 66.6 80 N.A. 73.3 N.A. 20 20 0 0
P-Site Similarity: 100 26.6 13.3 26.6 N.A. 73.3 73.3 N.A. 80 93.3 N.A. 80 N.A. 33.3 33.3 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 8 0 8 16 8 0 0 0 0 16 8 % A
% Cys: 0 8 0 8 8 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 0 8 31 0 8 0 8 0 0 16 8 0 8 % D
% Glu: 8 0 0 8 0 0 0 0 8 0 16 0 0 54 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 16 0 8 8 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 0 16 47 0 0 0 0 8 0 54 8 8 0 0 0 % I
% Lys: 39 8 8 0 0 16 0 24 0 0 31 24 0 8 0 % K
% Leu: 8 0 0 0 8 62 0 8 0 8 0 8 62 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 8 0 24 8 16 0 16 % N
% Pro: 8 0 0 0 8 8 0 0 0 8 8 0 0 0 0 % P
% Gln: 0 8 8 0 16 0 0 16 47 0 0 8 0 0 0 % Q
% Arg: 0 0 8 8 0 0 47 8 8 16 0 8 8 0 8 % R
% Ser: 8 8 0 8 24 0 8 8 0 0 0 24 0 8 39 % S
% Thr: 0 47 16 39 0 8 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 16 8 0 8 0 8 8 8 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _