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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXDN
All Species:
23.33
Human Site:
S374
Identified Species:
42.78
UniProt:
Q92626
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92626
NP_036425.1
1479
165275
S374
G
H
P
P
P
R
I
S
W
T
R
G
D
R
T
Chimpanzee
Pan troglodytes
XP_001169397
866
97623
Rhesus Macaque
Macaca mulatta
XP_001108296
1316
146985
R281
L
D
L
E
D
D
T
R
L
N
M
F
D
D
G
Dog
Lupus familis
XP_544073
1296
144318
E260
P
K
D
Q
V
V
L
E
E
H
T
V
E
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQ28
1475
165115
T371
G
H
P
L
P
Q
I
T
W
T
R
G
D
R
T
Rat
Rattus norvegicus
XP_002726775
1475
165020
T371
G
H
P
L
P
Q
I
T
W
T
R
G
D
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514779
1469
164647
S362
G
H
P
Q
P
L
I
S
W
S
R
G
N
G
E
Chicken
Gallus gallus
XP_419931
1456
163977
T350
G
H
P
Q
P
Q
I
T
W
T
K
G
D
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665312
1530
170912
T357
G
Q
P
Q
P
R
V
T
W
T
R
G
D
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZZ4
1527
170496
Q399
G
W
P
Q
P
D
I
Q
W
F
V
N
G
R
Q
Honey Bee
Apis mellifera
XP_396476
1293
147180
C258
G
G
T
I
S
F
T
C
E
V
I
G
D
P
I
Nematode Worm
Caenorhab. elegans
Q1ENI8
1285
146318
S250
L
T
C
A
K
N
S
S
S
K
L
V
V
W
M
Sea Urchin
Strong. purpuratus
XP_797821
1402
156847
S356
G
Y
P
L
P
R
I
S
W
T
K
E
G
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.4
56
55.8
N.A.
91
89.7
N.A.
65.4
83.4
N.A.
67.8
N.A.
41.5
40.7
36.1
46.5
Protein Similarity:
100
58.4
68.4
66.8
N.A.
94.6
93.2
N.A.
78.5
89.7
N.A.
80.3
N.A.
57.8
56.7
51
60.6
P-Site Identity:
100
0
6.6
0
N.A.
80
80
N.A.
60
73.3
N.A.
60
N.A.
40
20
6.6
53.3
P-Site Similarity:
100
0
6.6
13.3
N.A.
93.3
93.3
N.A.
73.3
93.3
N.A.
86.6
N.A.
40
20
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
16
0
0
0
0
0
0
54
8
0
% D
% Glu:
0
0
0
8
0
0
0
8
16
0
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
8
0
8
0
% F
% Gly:
70
8
0
0
0
0
0
0
0
0
0
54
16
8
8
% G
% His:
0
39
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
54
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
0
0
8
0
0
0
0
8
16
0
0
0
0
% K
% Leu:
16
0
8
24
0
8
8
0
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
8
8
0
8
% N
% Pro:
8
0
62
8
62
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
39
0
24
0
8
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
24
0
8
0
0
39
0
0
39
0
% R
% Ser:
0
0
0
0
8
0
8
31
8
8
0
0
0
0
8
% S
% Thr:
0
8
8
0
0
0
16
31
0
47
8
0
0
0
31
% T
% Val:
0
0
0
0
8
8
8
0
0
8
8
16
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
62
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _