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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDN All Species: 17.27
Human Site: S232 Identified Species: 31.67
UniProt: Q92626 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92626 NP_036425.1 1479 165275 S232 P R R I Q G R S V A T I T P E
Chimpanzee Pan troglodytes XP_001169397 866 97623
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 L145 Q P E T F G D L P K L E R L F
Dog Lupus familis XP_544073 1296 144318 R124 T L M I R N T R E S D Q G E Y
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 S229 P R R I Q G R S V A T I T P E
Rat Rattus norvegicus XP_002726775 1475 165020 S229 P R R I Q G R S V A T I T P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 T220 P R R F Q G R T I A S L T V E
Chicken Gallus gallus XP_419931 1456 163977 T213 G R S V A T I T P E E L N C E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 T215 T H T S G M L T V Y V N L C V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 G222 P Q M L Q N Q G F S S L G E H
Honey Bee Apis mellifera XP_396476 1293 147180 P122 N R L E Q I S P G A F S G L L
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 Y114 L A H N E L V Y I P P L C S D
Sea Urchin Strong. purpuratus XP_797821 1402 156847 T212 N A L G E V K T Q P V S L R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.4 56 55.8 N.A. 91 89.7 N.A. 65.4 83.4 N.A. 67.8 N.A. 41.5 40.7 36.1 46.5
Protein Similarity: 100 58.4 68.4 66.8 N.A. 94.6 93.2 N.A. 78.5 89.7 N.A. 80.3 N.A. 57.8 56.7 51 60.6
P-Site Identity: 100 0 6.6 6.6 N.A. 100 100 N.A. 60 13.3 N.A. 6.6 N.A. 13.3 20 0 0
P-Site Similarity: 100 0 6.6 20 N.A. 100 100 N.A. 86.6 33.3 N.A. 13.3 N.A. 53.3 20 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 8 0 0 0 0 39 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 16 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 8 % D
% Glu: 0 0 8 8 16 0 0 0 8 8 8 8 0 16 39 % E
% Phe: 0 0 0 8 8 0 0 0 8 0 8 0 0 0 8 % F
% Gly: 8 0 0 8 8 39 0 8 8 0 0 0 24 0 0 % G
% His: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 31 0 8 8 0 16 0 0 24 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % K
% Leu: 8 8 16 8 0 8 8 8 0 0 8 31 16 16 8 % L
% Met: 0 0 16 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 8 0 16 0 0 0 0 0 8 8 0 0 % N
% Pro: 39 8 0 0 0 0 0 8 16 16 8 0 0 24 0 % P
% Gln: 8 8 0 0 47 0 8 0 8 0 0 8 0 0 0 % Q
% Arg: 0 47 31 0 8 0 31 8 0 0 0 0 8 8 0 % R
% Ser: 0 0 8 8 0 0 8 24 0 16 16 16 0 8 0 % S
% Thr: 16 0 8 8 0 8 8 31 0 0 24 0 31 0 0 % T
% Val: 0 0 0 8 0 8 8 0 31 0 16 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _