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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM1
All Species:
22.42
Human Site:
Y420
Identified Species:
54.81
UniProt:
Q92611
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92611
NP_055489.1
657
73768
Y420
G
E
G
D
P
P
L
Y
V
N
V
N
M
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098603
657
73913
Y420
G
E
G
D
P
P
L
Y
V
N
V
N
M
F
S
Dog
Lupus familis
XP_533753
670
74870
Y433
G
E
G
D
P
P
L
Y
V
N
V
N
M
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
Y415
G
E
G
D
P
P
L
Y
V
N
V
N
M
F
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507359
465
53182
W242
S
G
Q
L
M
N
T
W
I
D
S
L
Q
A
F
Chicken
Gallus gallus
NP_001006143
616
69063
Y386
G
E
G
D
P
P
L
Y
V
N
V
N
M
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957483
524
59513
L301
L
L
V
E
F
G
I
L
S
R
L
I
G
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
K367
S
F
Y
E
Y
L
I
K
S
Y
V
Q
S
N
Y
Sea Urchin
Strong. purpuratus
XP_787584
508
57047
Y284
G
V
G
D
S
P
L
Y
V
N
V
N
M
N
T
Poplar Tree
Populus trichocarpa
XP_002321565
567
65048
S344
L
Q
A
T
A
N
S
S
H
R
E
F
V
H
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
85.8
N.A.
92.6
N.A.
N.A.
66.2
79.5
N.A.
59.8
N.A.
N.A.
N.A.
20.5
49.3
Protein Similarity:
100
N.A.
99
88
N.A.
95.2
N.A.
N.A.
68.6
84.7
N.A.
67.7
N.A.
N.A.
N.A.
36.3
62.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
93.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
20
100
N.A.
26.6
N.A.
N.A.
N.A.
20
80
Percent
Protein Identity:
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
60
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
50
0
20
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
10
0
50
10
% F
% Gly:
60
10
60
0
0
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
20
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
20
10
0
10
0
10
60
10
0
0
10
10
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
60
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
60
0
60
0
20
0
% N
% Pro:
0
0
0
0
50
60
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
0
10
10
20
0
10
0
10
0
50
% S
% Thr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
20
% T
% Val:
0
10
10
0
0
0
0
0
60
0
70
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
60
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _