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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM1
All Species:
18.18
Human Site:
T252
Identified Species:
44.44
UniProt:
Q92611
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92611
NP_055489.1
657
73768
T252
K
Q
P
F
G
D
M
T
I
K
D
Y
D
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098603
657
73913
T252
K
Q
P
F
G
D
M
T
I
K
D
Y
D
N
E
Dog
Lupus familis
XP_533753
670
74870
T265
K
Q
P
F
G
D
M
T
I
K
D
Y
D
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
T247
K
Q
P
F
G
D
M
T
I
E
D
Y
D
N
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507359
465
53182
P81
D
L
A
V
R
L
L
P
A
F
E
N
T
K
T
Chicken
Gallus gallus
NP_001006143
616
69063
T218
K
Q
P
F
G
D
M
T
I
K
D
Y
D
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957483
524
59513
L140
F
A
F
P
E
D
E
L
N
P
I
A
C
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
R206
K
D
K
Y
K
E
A
R
D
Y
I
E
N
N
F
Sea Urchin
Strong. purpuratus
XP_787584
508
57047
K123
A
P
P
D
Y
D
N
K
L
L
H
L
A
H
D
Poplar Tree
Populus trichocarpa
XP_002321565
567
65048
P183
F
L
P
A
F
D
T
P
T
G
L
P
Y
A
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
85.8
N.A.
92.6
N.A.
N.A.
66.2
79.5
N.A.
59.8
N.A.
N.A.
N.A.
20.5
49.3
Protein Similarity:
100
N.A.
99
88
N.A.
95.2
N.A.
N.A.
68.6
84.7
N.A.
67.7
N.A.
N.A.
N.A.
36.3
62.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
0
100
N.A.
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
13.3
100
N.A.
6.6
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
10
0
10
0
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
10
0
10
0
80
0
0
10
0
50
0
50
0
10
% D
% Glu:
0
0
0
0
10
10
10
0
0
10
10
10
0
10
50
% E
% Phe:
20
0
10
50
10
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
0
0
50
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
50
0
20
0
0
0
0
% I
% Lys:
60
0
10
0
10
0
0
10
0
40
0
0
0
10
0
% K
% Leu:
0
20
0
0
0
10
10
10
10
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
10
0
0
10
10
60
0
% N
% Pro:
0
10
70
10
0
0
0
20
0
10
0
10
0
0
0
% P
% Gln:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
50
10
0
0
0
10
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
10
10
0
0
0
0
10
0
50
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _