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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM1
All Species:
22.42
Human Site:
S219
Identified Species:
54.81
UniProt:
Q92611
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92611
NP_055489.1
657
73768
S219
T
V
S
F
D
K
D
S
T
V
Q
V
F
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098603
657
73913
S219
T
V
S
F
D
K
D
S
T
V
Q
V
F
E
A
Dog
Lupus familis
XP_533753
670
74870
S232
T
V
S
F
D
K
D
S
T
V
Q
V
F
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
S214
T
V
S
F
D
K
D
S
T
V
Q
V
F
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507359
465
53182
I48
S
L
L
S
A
H
R
I
I
I
D
S
K
Q
P
Chicken
Gallus gallus
NP_001006143
616
69063
S185
T
V
S
F
D
K
D
S
T
V
Q
V
F
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957483
524
59513
F107
Y
D
R
K
Y
S
S
F
P
D
A
L
K
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18788
590
66931
S173
P
M
S
K
K
P
N
S
Q
N
I
F
G
G
S
Sea Urchin
Strong. purpuratus
XP_787584
508
57047
S90
S
T
V
Q
V
F
E
S
T
I
R
I
I
G
G
Poplar Tree
Populus trichocarpa
XP_002321565
567
65048
T150
V
S
A
H
I
L
A
T
D
S
T
N
R
L
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
85.8
N.A.
92.6
N.A.
N.A.
66.2
79.5
N.A.
59.8
N.A.
N.A.
N.A.
20.5
49.3
Protein Similarity:
100
N.A.
99
88
N.A.
95.2
N.A.
N.A.
68.6
84.7
N.A.
67.7
N.A.
N.A.
N.A.
36.3
62.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
100
N.A.
0
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
26.6
100
N.A.
6.6
N.A.
N.A.
N.A.
33.3
46.6
Percent
Protein Identity:
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
10
0
0
0
10
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
50
0
50
0
10
10
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
50
0
% E
% Phe:
0
0
0
50
0
10
0
10
0
0
0
10
50
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
20
10
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
10
20
10
10
10
0
0
% I
% Lys:
0
0
0
20
10
50
0
0
0
0
0
0
20
0
10
% K
% Leu:
0
10
10
0
0
10
0
0
0
0
0
10
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
50
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
10
0
10
0
0
% R
% Ser:
20
10
60
10
0
10
10
70
0
10
0
10
0
0
10
% S
% Thr:
50
10
0
0
0
0
0
10
60
0
10
0
0
0
0
% T
% Val:
10
50
10
0
10
0
0
0
0
50
0
50
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _