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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D5
All Species:
17.58
Human Site:
S745
Identified Species:
35.15
UniProt:
Q92609
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92609
NP_001127852.1
795
89004
S745
L
R
T
L
R
S
T
S
G
K
S
Q
A
P
V
Chimpanzee
Pan troglodytes
XP_001161013
795
89000
S745
L
R
T
L
R
S
T
S
G
K
S
Q
A
P
V
Rhesus Macaque
Macaca mulatta
XP_001084887
797
89359
S747
L
R
T
L
R
S
S
S
G
K
S
Q
A
P
A
Dog
Lupus familis
XP_542771
803
90799
C750
L
R
T
L
R
S
T
C
G
R
S
E
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80XQ2
815
91834
S763
L
L
T
L
R
S
T
S
G
K
S
R
A
P
S
Rat
Rattus norvegicus
NP_001128234
805
90863
S755
L
L
T
L
R
N
T
S
G
K
S
R
V
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235030
780
87954
P731
F
K
E
S
A
V
K
P
E
A
P
S
R
P
L
Frog
Xenopus laevis
NP_001085083
800
90348
T751
D
V
V
K
E
D
P
T
E
T
N
Q
I
P
S
Zebra Danio
Brachydanio rerio
NP_956905
533
61527
L484
E
V
L
S
A
P
P
L
P
A
P
A
S
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731780
654
74319
F605
Y
Q
M
P
E
N
A
F
M
H
S
S
M
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497979
585
67014
L536
L
L
E
L
S
K
T
L
M
S
I
K
T
V
P
Sea Urchin
Strong. purpuratus
XP_799336
763
86968
E707
I
T
A
S
L
G
T
E
G
E
E
P
H
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
89.9
N.A.
87.6
87.1
N.A.
N.A.
78.2
69.2
49.8
N.A.
26.4
N.A.
29.6
36.2
Protein Similarity:
100
99.8
99
92.9
N.A.
91.4
91.6
N.A.
N.A.
86
80.5
58.1
N.A.
45.2
N.A.
43.9
56.6
P-Site Identity:
100
100
86.6
60
N.A.
80
66.6
N.A.
N.A.
6.6
13.3
0
N.A.
6.6
N.A.
20
13.3
P-Site Similarity:
100
100
93.3
73.3
N.A.
86.6
80
N.A.
N.A.
20
26.6
6.6
N.A.
20
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
0
9
0
0
17
0
9
34
0
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
17
0
17
0
0
9
17
9
9
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
59
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
9
0
9
0
9
9
0
0
42
0
9
0
0
0
% K
% Leu:
59
25
9
59
9
0
0
17
0
0
0
0
0
9
9
% L
% Met:
0
0
9
0
0
0
0
0
17
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
17
9
9
0
17
9
9
59
17
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
34
0
0
0
% Q
% Arg:
0
34
0
0
50
0
0
0
0
9
0
17
9
17
9
% R
% Ser:
0
0
0
25
9
42
9
42
0
9
59
17
9
0
17
% S
% Thr:
0
9
50
0
0
0
59
9
0
9
0
0
9
0
17
% T
% Val:
0
17
9
0
0
9
0
0
0
0
0
0
9
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _