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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D5
All Species:
26.06
Human Site:
S576
Identified Species:
52.12
UniProt:
Q92609
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92609
NP_001127852.1
795
89004
S576
I
S
R
S
R
S
H
S
K
T
M
G
R
K
E
Chimpanzee
Pan troglodytes
XP_001161013
795
89000
S576
I
S
R
S
R
S
H
S
K
T
M
G
R
K
E
Rhesus Macaque
Macaca mulatta
XP_001084887
797
89359
S578
I
S
R
S
R
S
H
S
K
T
M
G
R
K
E
Dog
Lupus familis
XP_542771
803
90799
F575
L
L
K
K
I
P
F
F
S
N
I
S
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80XQ2
815
91834
S600
I
A
R
S
R
S
H
S
K
T
M
G
R
K
E
Rat
Rattus norvegicus
NP_001128234
805
90863
S592
I
A
R
S
R
S
H
S
K
A
M
G
R
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235030
780
87954
S570
I
S
R
S
R
S
Q
S
K
T
M
S
R
K
E
Frog
Xenopus laevis
NP_001085083
800
90348
S585
I
S
R
S
R
S
H
S
K
S
Q
G
K
K
E
Zebra Danio
Brachydanio rerio
NP_956905
533
61527
G323
E
I
A
P
Q
I
Y
G
I
R
W
V
R
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731780
654
74319
A444
N
S
E
N
S
S
M
A
T
S
G
S
Q
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497979
585
67014
R375
V
K
L
A
R
H
Y
R
N
P
K
K
N
A
K
Sea Urchin
Strong. purpuratus
XP_799336
763
86968
K544
D
I
Q
T
R
D
L
K
V
L
S
K
S
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
89.9
N.A.
87.6
87.1
N.A.
N.A.
78.2
69.2
49.8
N.A.
26.4
N.A.
29.6
36.2
Protein Similarity:
100
99.8
99
92.9
N.A.
91.4
91.6
N.A.
N.A.
86
80.5
58.1
N.A.
45.2
N.A.
43.9
56.6
P-Site Identity:
100
100
100
6.6
N.A.
93.3
86.6
N.A.
N.A.
86.6
80
6.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
93.3
N.A.
N.A.
86.6
93.3
20
N.A.
46.6
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
9
0
0
0
9
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
59
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
9
50
0
0
0
% G
% His:
0
0
0
0
0
9
50
0
0
0
0
0
0
0
0
% H
% Ile:
59
17
0
0
9
9
0
0
9
0
9
0
0
9
9
% I
% Lys:
0
9
9
9
0
0
0
9
59
0
9
17
9
59
9
% K
% Leu:
9
9
9
0
0
0
9
0
0
9
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
50
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
9
9
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
9
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
59
0
75
0
0
9
0
9
0
0
67
0
9
% R
% Ser:
0
50
0
59
9
67
0
59
9
17
9
25
9
17
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
42
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _