KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D5
All Species:
27.88
Human Site:
S541
Identified Species:
55.76
UniProt:
Q92609
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92609
NP_001127852.1
795
89004
S541
K
N
I
S
S
S
P
S
V
E
S
L
P
G
G
Chimpanzee
Pan troglodytes
XP_001161013
795
89000
S541
K
N
I
S
S
S
P
S
V
E
S
L
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001084887
797
89359
S543
K
N
I
S
S
S
P
S
V
E
S
L
P
G
G
Dog
Lupus familis
XP_542771
803
90799
S540
L
S
M
K
K
F
I
S
L
P
A
V
F
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80XQ2
815
91834
S565
K
T
I
S
S
S
P
S
I
E
S
L
P
G
G
Rat
Rattus norvegicus
NP_001128234
805
90863
S557
K
T
I
S
S
S
P
S
M
E
S
L
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235030
780
87954
S535
S
K
I
S
S
S
P
S
I
E
S
L
P
G
G
Frog
Xenopus laevis
NP_001085083
800
90348
S550
K
N
M
S
S
S
P
S
I
E
S
L
P
G
G
Zebra Danio
Brachydanio rerio
NP_956905
533
61527
A288
Q
D
S
G
P
S
V
A
I
V
T
K
V
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731780
654
74319
P409
P
K
Q
F
E
Y
P
P
N
A
F
T
C
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497979
585
67014
R340
V
S
L
L
V
Q
I
R
H
L
L
L
S
S
D
Sea Urchin
Strong. purpuratus
XP_799336
763
86968
A509
R
I
G
K
G
A
N
A
Q
K
D
K
G
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
89.9
N.A.
87.6
87.1
N.A.
N.A.
78.2
69.2
49.8
N.A.
26.4
N.A.
29.6
36.2
Protein Similarity:
100
99.8
99
92.9
N.A.
91.4
91.6
N.A.
N.A.
86
80.5
58.1
N.A.
45.2
N.A.
43.9
56.6
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
80
86.6
6.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
40
N.A.
93.3
93.3
N.A.
N.A.
86.6
100
40
N.A.
6.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
17
0
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
9
0
0
0
0
59
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
9
0
0
0
0
9
0
9
0
0
% F
% Gly:
0
0
9
9
9
0
0
0
0
0
0
0
9
59
59
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
50
0
0
0
17
0
34
0
0
0
0
0
0
% I
% Lys:
50
17
0
17
9
0
0
0
0
9
0
17
0
0
9
% K
% Leu:
9
0
9
9
0
0
0
0
9
9
9
67
0
0
9
% L
% Met:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
0
0
9
0
9
0
0
0
0
9
0
% N
% Pro:
9
0
0
0
9
0
67
9
0
9
0
0
59
0
0
% P
% Gln:
9
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% R
% Ser:
9
17
9
59
59
67
0
67
0
0
59
0
9
25
9
% S
% Thr:
0
17
0
0
0
0
0
0
0
0
9
9
0
0
0
% T
% Val:
9
0
0
0
9
0
9
0
25
9
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _