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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D5
All Species:
24.24
Human Site:
S522
Identified Species:
48.48
UniProt:
Q92609
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92609
NP_001127852.1
795
89004
S522
Q
R
L
M
K
S
E
S
M
P
V
Q
L
N
K
Chimpanzee
Pan troglodytes
XP_001161013
795
89000
S522
Q
R
L
M
K
S
E
S
M
P
V
Q
L
N
K
Rhesus Macaque
Macaca mulatta
XP_001084887
797
89359
S524
Q
R
L
M
K
S
E
S
M
P
V
Q
L
N
K
Dog
Lupus familis
XP_542771
803
90799
K521
Q
Q
Q
Q
R
L
M
K
S
E
S
M
P
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80XQ2
815
91834
S546
Q
R
L
M
K
S
E
S
M
P
V
Q
L
N
K
Rat
Rattus norvegicus
NP_001128234
805
90863
S538
Q
R
L
M
K
S
E
S
M
P
V
Q
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235030
780
87954
E516
Q
Q
R
M
M
K
S
E
S
M
P
V
Q
L
G
Frog
Xenopus laevis
NP_001085083
800
90348
S531
Q
R
M
M
K
S
E
S
M
P
V
Q
L
S
K
Zebra Danio
Brachydanio rerio
NP_956905
533
61527
E269
R
E
V
R
K
G
K
E
E
M
L
T
S
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731780
654
74319
H390
Y
P
N
N
V
D
V
H
L
V
L
R
H
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_497979
585
67014
D321
L
W
D
V
L
L
I
D
R
P
I
A
P
L
A
Sea Urchin
Strong. purpuratus
XP_799336
763
86968
T490
V
P
V
V
K
K
T
T
S
A
V
S
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.2
89.9
N.A.
87.6
87.1
N.A.
N.A.
78.2
69.2
49.8
N.A.
26.4
N.A.
29.6
36.2
Protein Similarity:
100
99.8
99
92.9
N.A.
91.4
91.6
N.A.
N.A.
86
80.5
58.1
N.A.
45.2
N.A.
43.9
56.6
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
86.6
6.6
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
20
100
33.3
N.A.
20
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
50
17
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
67
17
9
9
0
0
0
0
0
0
50
% K
% Leu:
9
0
42
0
9
17
0
0
9
0
17
0
50
17
9
% L
% Met:
0
0
9
59
9
0
9
0
50
17
0
9
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
0
0
0
0
0
0
42
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
59
9
0
17
0
9
% P
% Gln:
67
17
9
9
0
0
0
0
0
0
0
50
17
0
9
% Q
% Arg:
9
50
9
9
9
0
0
0
9
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
50
9
50
25
0
9
9
9
9
0
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% T
% Val:
9
0
17
17
9
0
9
0
0
9
59
9
0
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _