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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK2
All Species:
38.48
Human Site:
T541
Identified Species:
84.67
UniProt:
Q92608
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92608
NP_004937.1
1830
211948
T541
L
M
K
E
D
G
T
T
L
H
D
G
F
H
D
Chimpanzee
Pan troglodytes
XP_527109
1830
211979
T541
L
M
K
E
D
G
T
T
L
H
D
G
F
H
D
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
T561
L
M
N
P
D
G
T
T
L
Q
D
G
R
H
D
Dog
Lupus familis
XP_546246
1849
214187
T550
L
M
K
E
D
G
T
T
L
Q
D
G
C
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3J5
1828
211715
T541
L
M
K
E
D
G
T
T
L
H
D
G
Y
H
E
Rat
Rattus norvegicus
XP_001068649
1831
211708
T541
L
M
K
E
D
G
T
T
L
Q
D
G
Y
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
T535
L
M
K
E
D
G
T
T
L
Q
D
G
S
H
D
Chicken
Gallus gallus
XP_425184
1893
219602
T521
L
M
K
E
D
G
T
T
L
Q
D
G
I
H
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103481
1866
215254
T542
L
M
R
Y
D
G
T
T
L
R
D
G
E
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477144
1970
226442
T562
L
M
Q
A
N
G
T
T
I
T
Q
G
Q
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
T547
L
M
T
D
I
G
T
T
I
T
N
G
I
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
54.2
94.7
N.A.
95
94
N.A.
90.9
81.9
N.A.
57.9
N.A.
37.9
N.A.
N.A.
45.3
Protein Similarity:
100
99.5
70.2
96.8
N.A.
97.4
97
N.A.
94.9
87.8
N.A.
73.5
N.A.
57.9
N.A.
N.A.
63.7
P-Site Identity:
100
100
73.3
86.6
N.A.
86.6
80
N.A.
86.6
86.6
N.A.
73.3
N.A.
46.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
73.3
86.6
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
80
N.A.
66.6
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
82
0
0
0
0
0
82
0
0
0
64
% D
% Glu:
0
0
0
64
0
0
0
0
0
0
0
0
10
0
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
28
0
0
0
100
0
% H
% Ile:
0
0
0
0
10
0
0
0
19
0
0
0
19
0
10
% I
% Lys:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
100
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% L
% Met:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
46
10
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
10
0
0
0
100
100
0
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _