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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPH1 All Species: 30.3
Human Site: Y89 Identified Species: 47.62
UniProt: Q92598 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92598 NP_006635.2 858 96865 Y89 K E K E N L S Y D L V P L K N
Chimpanzee Pan troglodytes XP_001142849 1091 122133 Y322 K E K E N L S Y D L V P L K N
Rhesus Macaque Macaca mulatta XP_001106968 840 94362 Y89 A E K S N L A Y D I V Q L P T
Dog Lupus familis XP_534515 1048 117305 Y278 K E K E N L S Y D L V P M K N
Cat Felis silvestris
Mouse Mus musculus Q61699 858 96389 Y89 K E K E N L S Y D L V P M K N
Rat Rattus norvegicus Q66HA8 858 96400 Y89 K E K E N L S Y D L V P M K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509055 859 95987 F89 K E K E K L S F D L I P M K N
Chicken Gallus gallus NP_001153170 856 96066 Y89 K E K E K L S Y D L V P M K N
Frog Xenopus laevis P02827 647 70897
Zebra Danio Brachydanio rerio NP_956151 840 94728 Y89 N L K P S L V Y D L A Q M P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VG58 641 70235
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q05036 776 86878 C89 R F I P F I P C K V V K L P N
Sea Urchin Strong. purpuratus Q06068 889 98600 Y89 K D A K V V P Y K I T Q L P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32589 693 77348 N33 I V V N E V S N R S T P S V V
Red Bread Mold Neurospora crassa O74225 707 78655 I48 F G P K S R Y I G E P A K T Q
Conservation
Percent
Protein Identity: 100 78.6 63.5 76.9 N.A. 93.4 92.4 N.A. 84.7 81.4 28.5 61.7 N.A. 27 N.A. 42 51.1
Protein Similarity: 100 78.6 77.9 79.6 N.A. 96.8 96.6 N.A. 92.5 90.7 45.7 77.3 N.A. 45.9 N.A. 58.9 67.9
P-Site Identity: 100 100 53.3 93.3 N.A. 93.3 93.3 N.A. 73.3 86.6 0 33.3 N.A. 0 N.A. 20 26.6
P-Site Similarity: 100 100 66.6 100 N.A. 100 100 N.A. 93.3 93.3 0 53.3 N.A. 0 N.A. 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.5 36.3
Protein Similarity: N.A. N.A. N.A. N.A. 51 53
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 7 0 0 0 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 60 0 0 0 0 0 0 % D
% Glu: 0 54 0 47 7 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 7 7 0 0 7 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 0 0 7 0 7 0 14 7 0 0 0 0 % I
% Lys: 54 0 60 14 14 0 0 0 14 0 0 7 7 47 0 % K
% Leu: 0 7 0 0 0 60 0 0 0 54 0 0 34 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % M
% Asn: 7 0 0 7 40 0 0 7 0 0 0 0 0 0 60 % N
% Pro: 0 0 7 14 0 0 14 0 0 0 7 54 0 27 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 7 % Q
% Arg: 7 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 14 0 54 0 0 7 0 0 7 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 14 0 0 7 7 % T
% Val: 0 7 7 0 7 14 7 0 0 7 54 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _