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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
10
Human Site:
Y846
Identified Species:
15.71
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
Y846
P
H
Q
N
G
E
C
Y
P
N
E
K
N
S
V
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
Y1079
P
H
Q
N
G
E
C
Y
P
N
E
K
N
S
V
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
S828
G
T
D
T
A
V
P
S
E
S
D
K
K
L
P
Dog
Lupus familis
XP_534515
1048
117305
Y1036
P
H
Q
N
G
E
C
Y
P
N
E
K
S
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
H846
P
H
Q
N
G
E
C
H
P
N
E
K
G
S
V
Rat
Rattus norvegicus
Q66HA8
858
96400
H846
P
H
Q
N
G
E
C
H
P
N
E
K
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
H846
P
Q
Q
N
G
D
C
H
P
G
D
K
N
P
D
Chicken
Gallus gallus
NP_001153170
856
96066
H844
P
Q
Q
N
G
E
C
H
P
G
D
Q
N
T
V
Frog
Xenopus laevis
P02827
647
70897
G636
C
G
A
Q
A
R
Q
G
G
N
S
G
P
T
I
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
A828
E
P
A
A
A
D
S
A
G
N
T
E
N
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
G630
G
Q
Q
A
G
G
F
G
G
Y
S
G
P
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
Q765
P
Q
P
A
A
G
D
Q
P
Q
S
Q
P
G
E
Sea Urchin
Strong. purpuratus
Q06068
889
98600
P877
S
K
E
G
E
T
K
P
D
E
T
K
P
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
E681
K
A
E
A
E
K
K
E
E
K
K
D
T
E
G
Red Bread Mold
Neurospora crassa
O74225
707
78655
D696
A
K
D
D
E
M
T
D
A
D
A
P
K
P
V
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
53.3
60
6.6
13.3
N.A.
20
N.A.
13.3
13.3
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
73.3
86.6
20
26.6
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
14
27
27
0
0
7
7
0
7
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
14
7
7
7
7
20
7
0
7
7
% D
% Glu:
7
0
14
0
20
40
0
7
14
7
34
7
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
14
7
0
7
54
14
0
14
20
14
0
14
14
7
7
% G
% His:
0
34
0
0
0
0
0
27
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% I
% Lys:
7
14
0
0
0
7
14
0
0
7
7
54
14
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
47
0
0
0
0
0
47
0
0
34
0
0
% N
% Pro:
54
7
7
0
0
0
7
7
54
0
0
7
27
14
14
% P
% Gln:
0
27
54
7
0
0
7
7
0
7
0
14
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
7
7
0
7
20
0
7
34
0
% S
% Thr:
0
7
0
7
0
7
7
0
0
0
14
0
7
20
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _