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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
34.24
Human Site:
Y726
Identified Species:
53.81
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
Y726
L
G
Q
R
L
Q
H
Y
A
K
I
A
A
D
F
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
Y959
L
G
Q
R
L
Q
H
Y
A
K
I
A
A
D
F
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y709
L
G
K
Q
I
Q
Q
Y
M
K
I
I
S
S
F
Dog
Lupus familis
XP_534515
1048
117305
Y916
L
G
Q
R
L
Q
H
Y
A
K
I
A
A
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
Y727
L
G
Q
R
L
Q
H
Y
A
K
I
A
A
D
F
Rat
Rattus norvegicus
Q66HA8
858
96400
Y727
L
G
Q
R
L
Q
H
Y
A
K
I
A
A
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
Y727
L
G
Q
R
L
Q
H
Y
A
K
I
A
G
D
Y
Chicken
Gallus gallus
NP_001153170
856
96066
Y726
L
G
H
R
L
Q
Y
Y
A
A
I
A
G
E
F
Frog
Xenopus laevis
P02827
647
70897
R536
D
D
D
A
Q
R
E
R
V
D
A
K
N
A
L
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y711
L
G
R
Q
L
Q
Q
Y
M
K
I
V
E
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
H530
Y
A
D
E
D
E
K
H
R
Q
R
I
T
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
I665
F
D
S
F
D
Q
S
I
M
R
V
R
K
A
Y
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y744
F
G
K
A
L
V
P
Y
I
K
T
L
D
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
L581
L
E
E
Y
I
Y
T
L
R
G
K
L
E
E
E
Red Bread Mold
Neurospora crassa
O74225
707
78655
L596
L
D
D
Q
Y
A
D
L
A
S
E
E
E
K
E
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
46.6
100
N.A.
100
100
N.A.
86.6
66.6
0
46.6
N.A.
0
N.A.
6.6
26.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
93.3
80
6.6
66.6
N.A.
20
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
0
7
0
0
54
7
7
47
34
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
20
20
0
14
0
7
0
0
7
0
0
7
40
0
% D
% Glu:
0
7
7
7
0
7
7
0
0
0
7
7
20
14
14
% E
% Phe:
14
0
0
7
0
0
0
0
0
0
0
0
0
0
47
% F
% Gly:
0
67
0
0
0
0
0
0
0
7
0
0
14
0
0
% G
% His:
0
0
7
0
0
0
40
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
14
0
0
7
7
0
60
14
0
0
0
% I
% Lys:
0
0
14
0
0
0
7
0
0
60
7
7
7
7
0
% K
% Leu:
74
0
0
0
60
0
0
14
0
0
0
14
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
40
20
7
67
14
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
7
47
0
7
0
7
14
7
7
7
0
0
7
% R
% Ser:
0
0
7
0
0
0
7
0
0
7
0
0
7
14
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
0
7
0
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
7
7
7
67
0
0
0
0
0
0
27
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _