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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
35.15
Human Site:
Y446
Identified Species:
55.24
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
Y446
P
F
E
L
E
A
F
Y
S
D
P
Q
G
V
P
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
Y679
P
F
E
L
E
A
F
Y
S
D
P
Q
G
V
P
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y446
P
F
T
L
E
A
Y
Y
S
S
P
Q
D
L
P
Dog
Lupus familis
XP_534515
1048
117305
Y635
P
F
E
L
E
A
F
Y
S
D
P
Q
G
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
Y446
P
F
E
L
E
A
F
Y
S
D
P
Q
G
V
P
Rat
Rattus norvegicus
Q66HA8
858
96400
Y446
P
F
E
L
E
A
F
Y
S
D
P
Q
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
Y446
P
F
E
L
E
A
F
Y
S
D
P
A
G
V
P
Chicken
Gallus gallus
NP_001153170
856
96066
Y446
P
F
E
L
E
A
F
Y
S
D
P
N
G
V
P
Frog
Xenopus laevis
P02827
647
70897
P317
L
F
R
G
T
L
E
P
V
E
K
A
L
R
D
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y446
P
F
T
L
D
A
Y
Y
N
S
P
K
E
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
T311
C
A
D
L
F
R
N
T
L
Q
P
V
E
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
A446
S
G
P
F
N
V
E
A
H
Y
A
Q
P
N
V
Sea Urchin
Strong. purpuratus
Q06068
889
98600
A446
F
E
L
V
A
R
Y
A
D
P
N
L
P
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
L362
S
E
A
F
G
K
P
L
S
T
T
L
N
Q
D
Red Bread Mold
Neurospora crassa
O74225
707
78655
S377
I
A
R
G
C
A
F
S
C
A
I
L
S
P
V
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
66.6
100
N.A.
100
93.3
N.A.
93.3
93.3
6.6
46.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
80
100
N.A.
100
93.3
N.A.
93.3
93.3
13.3
80
N.A.
20
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
0
7
67
0
14
0
7
7
14
7
0
7
% A
% Cys:
7
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
0
7
47
0
0
7
0
14
% D
% Glu:
0
14
47
0
54
0
14
0
0
7
0
0
14
0
0
% E
% Phe:
7
67
0
14
7
0
54
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
14
7
0
0
0
0
0
0
0
40
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
7
7
0
7
0
% K
% Leu:
7
0
7
67
0
7
0
7
7
0
0
20
7
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
7
0
7
7
7
7
0
% N
% Pro:
60
0
7
0
0
0
7
7
0
7
67
0
14
7
67
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
47
0
7
0
% Q
% Arg:
0
0
14
0
0
14
0
0
0
0
0
0
0
7
0
% R
% Ser:
14
0
0
0
0
0
0
7
60
14
0
0
7
0
0
% S
% Thr:
0
0
14
0
7
0
0
7
0
7
7
0
0
0
0
% T
% Val:
0
0
0
7
0
7
0
0
7
0
0
7
0
47
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
60
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _