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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
38.48
Human Site:
Y252
Identified Species:
60.48
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
Y252
C
A
E
F
K
T
K
Y
K
L
D
A
K
S
K
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
Y485
C
A
E
F
K
T
K
Y
K
L
D
A
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Dog
Lupus familis
XP_534515
1048
117305
Y441
C
T
E
F
K
T
K
Y
K
L
D
A
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
Y252
C
A
E
F
K
T
K
Y
K
L
D
A
K
S
K
Rat
Rattus norvegicus
Q66HA8
858
96400
Y252
C
A
E
F
K
T
K
Y
K
L
D
A
K
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
Y252
C
A
E
I
Q
A
K
Y
K
L
D
P
R
S
K
Chicken
Gallus gallus
NP_001153170
856
96066
Y252
C
A
E
I
K
A
K
Y
K
L
D
P
K
S
K
Frog
Xenopus laevis
P02827
647
70897
A134
K
M
K
E
T
A
E
A
Y
L
G
H
P
V
T
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y252
C
E
E
F
V
V
K
Y
K
L
D
A
K
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
A128
L
T
K
M
K
E
T
A
E
A
Y
L
G
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
Y254
R
K
E
F
K
T
K
Y
G
I
D
A
A
T
S
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y252
A
V
D
F
Q
T
R
Y
K
M
D
V
K
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
G179
V
N
D
V
T
A
A
G
V
S
Y
G
I
F
K
Red Bread Mold
Neurospora crassa
O74225
707
78655
P194
L
P
G
P
E
E
K
P
R
R
V
A
F
V
D
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
73.3
93.3
N.A.
100
100
N.A.
66.6
80
6.6
73.3
N.A.
6.6
N.A.
53.3
46.6
P-Site Similarity:
100
100
73.3
93.3
N.A.
100
100
N.A.
80
80
20
80
N.A.
20
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
40
0
0
0
27
7
14
0
7
0
54
7
0
0
% A
% Cys:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
0
0
0
0
0
0
74
0
0
0
7
% D
% Glu:
0
14
67
7
7
14
7
0
7
0
0
0
0
7
0
% E
% Phe:
0
0
0
60
0
0
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
7
0
7
0
0
7
7
0
7
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
0
0
7
0
7
7
0
0
% I
% Lys:
7
7
14
0
54
7
74
0
67
0
0
0
60
0
67
% K
% Leu:
14
0
0
0
0
0
0
0
0
67
0
7
0
0
0
% L
% Met:
0
7
0
7
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
0
7
0
0
0
7
0
0
0
14
7
0
0
% P
% Gln:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
7
0
7
7
0
0
7
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
0
60
14
% S
% Thr:
0
14
0
0
14
47
7
0
0
0
0
0
0
14
7
% T
% Val:
7
7
0
7
7
7
0
0
7
0
7
7
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
7
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _