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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
25.45
Human Site:
T670
Identified Species:
40
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
T670
Q
N
F
L
R
L
L
T
E
T
E
D
W
L
Y
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
T903
Q
N
F
L
R
L
L
T
E
T
E
D
W
L
Y
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
E653
N
S
F
T
L
K
L
E
D
T
E
N
W
L
Y
Dog
Lupus familis
XP_534515
1048
117305
T860
Q
N
F
L
R
L
L
T
E
T
E
N
W
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
T671
E
K
F
L
R
L
L
T
E
T
E
D
W
L
Y
Rat
Rattus norvegicus
Q66HA8
858
96400
T671
E
K
F
L
R
L
L
T
E
T
E
D
W
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
T671
Q
S
F
L
R
L
L
T
E
T
E
D
W
L
Y
Chicken
Gallus gallus
NP_001153170
856
96066
T670
Q
G
F
S
A
L
L
T
E
T
E
G
W
L
Y
Frog
Xenopus laevis
P02827
647
70897
A491
N
G
I
L
N
V
S
A
V
E
K
S
S
G
K
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
E655
D
V
L
S
L
K
L
E
D
T
E
V
W
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
N485
L
D
A
N
G
I
L
N
V
S
A
K
E
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
D620
S
T
E
D
W
L
Y
D
E
G
E
D
A
E
R
Sea Urchin
Strong. purpuratus
Q06068
889
98600
E688
G
S
F
S
K
L
L
E
E
T
E
N
W
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
V536
K
K
D
D
L
T
I
V
A
H
T
F
G
L
D
Red Bread Mold
Neurospora crassa
O74225
707
78655
K551
P
S
L
D
P
A
A
K
N
A
A
I
E
R
E
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
46.6
93.3
N.A.
86.6
86.6
N.A.
93.3
73.3
6.6
40
N.A.
6.6
N.A.
26.6
60
P-Site Similarity:
100
100
66.6
100
N.A.
93.3
93.3
N.A.
100
73.3
20
46.6
N.A.
33.3
N.A.
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
7
7
7
7
14
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
20
0
0
0
7
14
0
0
40
0
0
7
% D
% Glu:
14
0
7
0
0
0
0
20
60
7
74
0
14
7
7
% E
% Phe:
0
0
60
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
14
0
0
7
0
0
0
0
7
0
7
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
0
0
0
0
7
0
0
0
% I
% Lys:
7
20
0
0
7
14
0
7
0
0
7
7
0
0
7
% K
% Leu:
7
0
14
47
20
60
74
0
0
0
0
0
0
74
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
14
20
0
7
7
0
0
7
7
0
0
20
0
0
0
% N
% Pro:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
40
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
7
27
0
20
0
0
7
0
0
7
0
7
7
0
7
% S
% Thr:
0
7
0
7
0
7
0
47
0
67
7
0
0
0
0
% T
% Val:
0
7
0
0
0
7
0
7
14
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
67
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _