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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
22.73
Human Site:
T561
Identified Species:
35.71
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
T561
S
P
P
S
P
E
L
T
S
E
E
N
K
I
P
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
T794
S
P
P
S
P
E
L
T
S
E
E
N
K
I
P
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
M561
A
G
S
K
D
K
K
M
D
Q
P
P
Q
A
K
Dog
Lupus familis
XP_534515
1048
117305
T751
S
P
P
S
P
E
L
T
S
E
E
N
K
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
T562
S
P
P
S
P
E
L
T
S
E
E
S
K
T
P
Rat
Rattus norvegicus
Q66HA8
858
96400
T562
S
P
P
S
P
E
L
T
S
E
E
N
K
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
P562
S
P
P
P
P
E
P
P
S
E
E
H
K
I
P
Chicken
Gallus gallus
NP_001153170
856
96066
P561
S
P
P
S
S
E
P
P
S
E
E
N
K
I
P
Frog
Xenopus laevis
P02827
647
70897
T430
T
K
Q
T
Q
S
F
T
T
Y
S
D
N
Q
P
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
P567
E
K
K
S
D
Q
P
P
Q
A
K
K
P
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
K424
R
I
P
C
K
Q
T
K
T
F
S
T
Y
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
L559
D
V
Q
K
F
H
N
L
E
L
Q
M
Q
E
S
Sea Urchin
Strong. purpuratus
Q06068
889
98600
S581
S
S
K
S
D
K
E
S
K
D
Q
N
S
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
S475
Q
L
P
E
G
Q
D
S
V
P
V
K
L
K
L
Red Bread Mold
Neurospora crassa
O74225
707
78655
G490
K
A
R
I
N
I
H
G
I
L
N
V
E
S
A
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
0
100
N.A.
86.6
100
N.A.
73.3
80
13.3
6.6
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
100
N.A.
80
80
40
20
N.A.
20
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
7
0
0
0
7
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
20
0
7
0
7
7
0
7
0
0
7
% D
% Glu:
7
0
0
7
0
47
7
0
7
47
47
0
7
14
0
% E
% Phe:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
7
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
7
0
7
0
0
7
0
0
0
0
40
0
% I
% Lys:
7
14
14
14
7
14
7
7
7
0
7
14
47
14
7
% K
% Leu:
0
7
0
0
0
0
34
7
0
14
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
7
40
7
0
0
% N
% Pro:
0
47
60
7
40
0
20
20
0
7
7
7
7
0
54
% P
% Gln:
7
0
14
0
7
20
0
0
7
7
14
0
14
7
0
% Q
% Arg:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
54
7
7
54
7
7
0
14
47
0
14
7
7
14
7
% S
% Thr:
7
0
0
7
0
0
7
40
14
0
0
7
0
7
0
% T
% Val:
0
7
0
0
0
0
0
0
7
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _