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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
17.88
Human Site:
T527
Identified Species:
28.1
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
T527
R
P
P
E
N
P
D
T
D
K
N
V
Q
Q
D
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
T760
R
P
P
E
N
P
D
T
D
K
N
V
Q
Q
D
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
E527
E
K
M
Q
V
D
Q
E
E
P
H
V
E
E
Q
Dog
Lupus familis
XP_534515
1048
117305
T717
R
P
A
E
N
L
D
T
D
K
N
I
Q
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
V528
R
P
T
E
S
S
D
V
D
K
N
I
Q
Q
D
Rat
Rattus norvegicus
Q66HA8
858
96400
V528
K
P
A
E
S
S
D
V
D
K
N
I
Q
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
S528
R
P
A
E
N
S
D
S
D
K
N
V
Q
Q
D
Chicken
Gallus gallus
NP_001153170
856
96066
S527
Q
M
P
A
E
N
S
S
D
K
N
N
Q
Q
E
Frog
Xenopus laevis
P02827
647
70897
D396
V
Q
D
L
L
L
L
D
V
A
P
L
S
L
G
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
T533
V
D
Q
E
E
Q
K
T
P
E
T
E
Q
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
L390
S
G
K
I
Q
D
V
L
L
V
D
V
A
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
A525
D
A
K
T
E
A
P
A
E
P
L
E
P
V
K
Sea Urchin
Strong. purpuratus
Q06068
889
98600
E547
Q
G
G
A
G
E
G
E
A
S
A
D
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
M441
N
R
T
G
D
F
S
M
A
A
S
Y
T
D
I
Red Bread Mold
Neurospora crassa
O74225
707
78655
T456
P
E
E
L
P
G
K
T
S
P
F
I
G
R
F
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
6.6
80
N.A.
66.6
60
N.A.
80
40
0
20
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
40
86.6
N.A.
80
80
N.A.
86.6
60
6.6
40
N.A.
13.3
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
20
14
0
7
0
7
14
14
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
7
14
40
7
47
0
7
7
0
7
40
% D
% Glu:
7
7
7
47
20
7
0
14
14
7
0
14
7
20
14
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
14
7
7
7
7
7
0
0
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
27
0
0
7
% I
% Lys:
7
7
14
0
0
0
14
0
0
47
0
0
7
0
7
% K
% Leu:
0
0
0
14
7
14
7
7
7
0
7
7
0
7
7
% L
% Met:
0
7
7
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
27
7
0
0
0
0
47
7
0
0
7
% N
% Pro:
7
40
20
0
7
14
7
0
7
20
7
0
7
7
0
% P
% Gln:
14
7
7
7
7
7
7
0
0
0
0
0
54
47
7
% Q
% Arg:
34
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
0
0
0
14
20
14
14
7
7
7
0
7
0
0
% S
% Thr:
0
0
14
7
0
0
0
34
0
0
7
0
7
0
0
% T
% Val:
14
0
0
0
7
0
7
14
7
7
0
34
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _