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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
23.64
Human Site:
S746
Identified Species:
37.14
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
S746
K
Y
N
H
I
D
E
S
E
M
K
K
V
E
K
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
S979
K
Y
N
H
I
D
E
S
E
M
K
K
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
A729
Q
Y
D
H
L
D
A
A
D
M
T
K
V
E
K
Dog
Lupus familis
XP_534515
1048
117305
S936
K
Y
N
H
I
D
E
S
E
M
K
K
V
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
S747
K
Y
N
H
I
D
E
S
E
M
K
K
V
E
K
Rat
Rattus norvegicus
Q66HA8
858
96400
S747
K
Y
N
H
I
D
E
S
E
M
K
K
V
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
T747
K
Y
I
H
V
D
A
T
E
M
K
K
V
E
K
Chicken
Gallus gallus
NP_001153170
856
96066
M746
K
Y
I
H
I
D
E
M
E
M
M
K
V
E
K
Frog
Xenopus laevis
P02827
647
70897
D556
N
L
K
S
M
V
E
D
E
N
V
K
G
K
I
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
A731
Q
Y
D
H
L
E
E
A
E
I
Q
K
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
S550
Y
V
F
N
V
K
Q
S
V
E
Q
A
P
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
L685
G
G
P
T
Y
A
H
L
D
S
K
E
M
E
K
Sea Urchin
Strong. purpuratus
Q06068
889
98600
E764
K
Y
S
H
I
E
K
E
D
M
A
K
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
L601
S
D
A
E
K
T
K
L
Q
G
M
L
N
K
A
Red Bread Mold
Neurospora crassa
O74225
707
78655
L616
L
M
E
V
E
D
W
L
Y
D
E
G
D
D
A
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
53.3
100
N.A.
100
100
N.A.
73.3
80
20
46.6
N.A.
6.6
N.A.
20
60
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
86.6
80
33.3
100
N.A.
33.3
N.A.
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
14
14
0
0
7
7
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
0
0
60
0
7
20
7
0
0
7
14
0
% D
% Glu:
0
0
7
7
7
14
54
7
60
7
7
7
0
67
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
0
0
7
0
7
7
0
7
% G
% His:
0
0
0
67
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
0
47
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
54
0
7
0
7
7
14
0
0
0
47
74
0
14
74
% K
% Leu:
7
7
0
0
14
0
0
20
0
0
0
7
0
0
0
% L
% Met:
0
7
0
0
7
0
0
7
0
60
14
0
7
0
0
% M
% Asn:
7
0
34
7
0
0
0
0
0
7
0
0
7
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
14
0
0
0
0
0
7
0
7
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
7
0
0
0
40
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
7
0
7
0
0
7
0
0
0
0
% T
% Val:
0
7
0
7
14
7
0
0
7
0
7
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
67
0
0
7
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _