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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPH1
All Species:
27.88
Human Site:
S557
Identified Species:
43.81
UniProt:
Q92598
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92598
NP_006635.2
858
96865
S557
Q
T
S
Q
S
P
P
S
P
E
L
T
S
E
E
Chimpanzee
Pan troglodytes
XP_001142849
1091
122133
S790
Q
T
S
Q
S
P
P
S
P
E
L
T
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
K557
E
T
S
Q
A
G
S
K
D
K
K
M
D
Q
P
Dog
Lupus familis
XP_534515
1048
117305
S747
Q
T
S
Q
S
P
P
S
P
E
L
T
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61699
858
96389
S558
Q
T
S
Q
S
P
P
S
P
E
L
T
S
E
E
Rat
Rattus norvegicus
Q66HA8
858
96400
S558
Q
T
S
Q
S
P
P
S
P
E
L
T
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509055
859
95987
P558
Q
T
P
Q
S
P
P
P
P
E
P
P
S
E
E
Chicken
Gallus gallus
NP_001153170
856
96066
S557
Q
T
S
Q
S
P
P
S
S
E
P
P
S
E
E
Frog
Xenopus laevis
P02827
647
70897
T426
T
T
I
P
T
K
Q
T
Q
S
F
T
T
Y
S
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
S563
E
G
K
Q
E
K
K
S
D
Q
P
P
Q
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VG58
641
70235
C420
E
R
N
C
R
I
P
C
K
Q
T
K
T
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
K555
P
V
S
Y
D
V
Q
K
F
H
N
L
E
L
Q
Sea Urchin
Strong. purpuratus
Q06068
889
98600
S577
Q
T
S
E
S
S
K
S
D
K
E
S
K
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32589
693
77348
E471
I
T
G
V
Q
L
P
E
G
Q
D
S
V
P
V
Red Bread Mold
Neurospora crassa
O74225
707
78655
I486
I
C
K
L
K
A
R
I
N
I
H
G
I
L
N
Conservation
Percent
Protein Identity:
100
78.6
63.5
76.9
N.A.
93.4
92.4
N.A.
84.7
81.4
28.5
61.7
N.A.
27
N.A.
42
51.1
Protein Similarity:
100
78.6
77.9
79.6
N.A.
96.8
96.6
N.A.
92.5
90.7
45.7
77.3
N.A.
45.9
N.A.
58.9
67.9
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
73.3
80
13.3
13.3
N.A.
6.6
N.A.
6.6
33.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
73.3
80
33.3
33.3
N.A.
33.3
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.5
36.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51
53
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
20
0
7
0
7
7
0
% D
% Glu:
20
0
0
7
7
0
0
7
0
47
7
0
7
47
47
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% F
% Gly:
0
7
7
0
0
7
0
0
7
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
14
0
7
0
0
7
0
7
0
7
0
0
7
0
0
% I
% Lys:
0
0
14
0
7
14
14
14
7
14
7
7
7
0
7
% K
% Leu:
0
0
0
7
0
7
0
0
0
0
34
7
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
7
0
0
0
7
% N
% Pro:
7
0
7
7
0
47
60
7
40
0
20
20
0
7
7
% P
% Gln:
54
0
0
60
7
0
14
0
7
20
0
0
7
7
14
% Q
% Arg:
0
7
0
0
7
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
60
0
54
7
7
54
7
7
0
14
47
0
14
% S
% Thr:
7
74
0
0
7
0
0
7
0
0
7
40
14
0
0
% T
% Val:
0
7
0
7
0
7
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _